CHANGE IN MACROMOLECULAR-COMPOSITION OF INTERSTITIAL FLUID FROM SWOLLEN ARMS AFTER BREAST-CANCER-TREATMENT, AND ITS IMPLICATIONS
CHANGE IN MACROMOLECULAR-COMPOSITION OF INTERSTITIAL FLUID FROM SWOLLEN ARMS AFTER BREAST-CANCER-TREATMENT, AND ITS IMPLICATIONS
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DOI：
10.1042/cs0850737
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发表时间：
1993-12-01
期刊：
影响因子：
6
通讯作者：
MORTIMER, PS
中科院分区：
文献类型：
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作者：
BATES, DO;LEVICK, JR;MORTIMER, PS
1.乳腺癌治疗后慢性手臂水肿的病理生理学进行了研究，通过收集血清和皮下间质液从受影响的和对侧的手臂灯芯法（双臂）和抽吸（水肿的手臂）。分析体液中的总蛋白、白蛋白、糖胺聚糖和粘度，并测量手臂体积.抽吸水肿液中的总蛋白浓度为32.4+/-7.5 g/l（整个过程中的平均值+/-SD; n=39）。来自水肿臂的芯吸液中的蛋白质浓度（35.8+/-7.3 g/l，n = 14）与抽吸液中的蛋白质浓度无显著差异。水肿蛋白浓度显著低于非肿胀臂的吸液芯液（41.4+/-6.7 cmH 2 O，n=13，P
1. The pathophysiology of chronic arm oedema after treatment of breast cancer was investigated by collecting serum and subcutaneous interstitial fluid from the affected and contralateral arms by the wick method (both arms) and by aspiration (oedematous arm). The fluids were analysed for total protein, albumin, glycosaminoglycan and viscosity, and arm volume was measured.2. Total protein concentration in the aspirated oedema fluid was 32.4+/-7.5 g/l (mean+/-SD throughout; n=39). Protein concentration in wick fluid from the oedematous arm (35.8+/-7.3 g/l, n = 14) was not significantly different from that in aspirated fluid. The oedema protein concentrations were significantly lower than in wick fluid from the non-swollen arm (41.4+/-6.7 cmH2O, n=13, P