Concurrent PCP and TB pneumonia in HIV infected patients
Concurrent PCP and TB pneumonia in HIV infected patients
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DOI：
10.1080/00365540701472056
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发表时间：
2007-01-01
影响因子：
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通讯作者：
Boulanger, Catherine
中科院分区：
文献类型：
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作者：
Castro, Jose G.;Manzi, Gabriel;Boulanger, Catherine
我们的目的是评估艾滋病毒感染并发肺孢子虫肺炎（PCP）和结核病（TB）患者的发病率和临床特征。我们对1995年至2004年在迈阿密的一家大型县医院同一住院期间因肺结核和PCP住院的HIV感染患者进行了回顾性记录审查。2651例HIV感染和可能的TB或PCP患者被确定。有99例PCP病例（81例推定病例和18例确诊病例），35例为结核病新病例。有17名患者同时诊断为肺结核和PCP。这些患者中约有一半不知道自己感染了艾滋病毒，其中一半的痰液中AFB呈阴性。大多数是男性，CD 4计数低于100个细胞/mm（3）。胸部X线显示，在大多数情况下，双侧浸润。除2人外，其余均存活入院。因此，在研究期间，在佛罗里达迈阿密的这家大型县级医院，HIV感染患者并发结核病和PCP并不罕见，但其诊断具有挑战性。
We aimed to assess the incidence and clinical characteristics of patients with HIV infection with concurrent Pneumocystis pneumonia (PCP) and tuberculosis (TB). We carried out a retrospective record review of HIV infected patients admitted with pulmonary TB and PCP during the same hospital admission at a large county hospital in Miami, from 1995 to 2004. 2651 patients with HIV infection and possible TB or PCP were identified. There were 99 cases of PCP (81 presumptive and 18 confirmed) and 35 were new cases of TB. There were 17 patients who had a new, concurrent diagnosis of pulmonary TB and PCP. Approximately half of these patients were unaware of their HIV infections and half of them had a negative AFB in sputum. Most were men and had a CD4 count less than 100 cells/mm(3). Chest X-ray disclosed bilateral infiltrates in most of the cases. All but 2 survived the hospital admission. Thus, concurrent TB and PCP in HIV infected patients were not uncommon in this large county hospital in Miami, Florida in the studied period, but its diagnosis was challenging.