Multidetector-Row Computed Tomography in Evaluation of Atherosclerotic Carotid Plaques Complicated with Intraplaque Hemorrhage
Multidetector-Row Computed Tomography in Evaluation of Atherosclerotic Carotid Plaques Complicated with Intraplaque Hemorrhage
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DOI：
10.1016/j.avsg.2008.05.008
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发表时间：
2009-03-01
影响因子：
1.5
通讯作者：
Brkljacic, Boris
中科院分区：
文献类型：
--
作者：
Ajduk, Marko;Pavic, Ladislav;Brkljacic, Boris
我们的目的是确定多排CT在检测颈动脉粥样硬化斑块合并斑块内出血中的敏感性和特异性。我们检查了31例颈动脉狭窄手术患者的颈动脉斑块。将颈动脉斑块的术前多排CT分析结果与相同斑块区域的组织学分析结果进行比较。在多层螺旋CT检查后1周内进行颈动脉内膜切除术。采用美国心脏协会动脉粥样硬化斑块分类进行组织学分类。颈动脉斑块合并斑块内出血的中位组织密度为22个Houns场单位（HU）。无并发症斑块的非钙化节段的中位组织密度为59 HU（p = 0.0062）。观察到的复杂斑块的最高组织密度为31 HU。多排螺旋CT以组织密度31 HU为阈值，检出斑块合并出血的敏感性为100%，特异性为64.7%。多层螺旋CT显示高水平的敏感性和中等水平的特异性。city在检测颈动脉粥样硬化斑块合并出血中的应用。
Our aim was to determine the sensitivity and specificity of multidetector-row computed tomography (CT) in detecting atherosclerotic carotid plaques complicated with intraplaque hemorrhage. We examined carotid plaques from 31 patients operated for carotid artery stenosis. Results of preoperative multidetector-row CT analysis of carotid plaques were compared with results of histological analysis of the same plaque areas. Carotid endarterectomy was performed within 1 week of multidetector-row CT. American Heart Association classification of atherosclerotic plaques was applied for histological classification. Median tissue density of carotid plaques complicated with intraplaque hemorrhage was 22 Houns field units (HU). Median tissue density of noncalcified segments of uncomplicated plaques was 59 HU (p = 0.0062). The highest tissue density observed for complicated plaques was 31 HU. Multidetector-row CT detected plaques complicated with hemorrhage with sensitivity of 100% and specificity of 64.7%, with tissue density of 31 HU as a threshold value. Multidetector-row CT showed a high level of sensitivity and a moderate level of speci. city in detecting atherosclerotic carotid plaques complicated with hemorrhage.