One-pot synthesis of γ-diketones, γ-keto esters, and conjugated cyclopentenones from nitroalkanes
One-pot synthesis of γ-diketones, γ-keto esters, and conjugated cyclopentenones from nitroalkanes
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DOI：
10.1055/s-2002-35993
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发表时间：
2002-12-01
影响因子：
2.6
通讯作者：
Fiorini, D
中科院分区：
文献类型：
--
作者：
Ballini, R;Barboni, L;Fiorini, D
在两种等效DBU的存在下，将伯硝基烷烃共轭加成至α， β -不饱和酮或α， β -不饱和酯，可以一锅分别制备-二酮或-酮酯。用2-芳基-1-硝基乙烷衍生物作为硝基烷烃与α反应的起始物。-不饱和酮，环戊烯酮的一锅形成被观察到。
Conjugated addition of primary nitroalkanes to alpha,beta-unsaturated ketones or alpha,beta-unsaturated esters, in the presence of two equivalents of DBU, allows the one-pot prepration of gamma-diketones or gamma-keto esters, respectively. When 2-aryl-1-nitroethane derivatives are employed as starting nitroalkanes in the reaction with alpha.beta-unsaturated ketones, the one-pot formation of cyclopentenones is observed.