Prevalence of stroke in an urban, mixed-income community in Lagos, Nigeria

Prevalence of stroke in an urban, mixed-income community in Lagos, Nigeria
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DOI:
10.1159/000108114
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发表时间:
2007-01-01
期刊:
影响因子:
5.7
通讯作者:
Ojini, Frank
Ojini, Frank
中科院分区:
医学3区
文献类型:
--
作者:
Danesi, Mustapha;Okubadejo, Njideka;Ojini, Frank

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背景:发展中国家的脑血管疾病负担预计将呈上升趋势。然而,目前非洲中风流行病学的数据很少。方法:采用三阶段方法,我们在尼日利亚拉各斯的一个城市混合收入社区进行了挨家挨户的中风研究。我们在第一阶段使用了对WHO方案的修改,在第二阶段使用了卒中特异性问卷,在第三阶段对所有卒中筛查呈阳性的人进行了神经学检查。我们还检查了相同数量的中风阴性者。结果:总体而言,尼日利亚城市中风的粗患病率为1.14/ 1000(男性:1.51,女性:0.69)。根据美国2000年人口年龄调整后的10岁中期患病率,随着年龄的增长,患病率呈上升趋势:35 ~ 44岁= 0.009,45 ~ 54岁= 0.33,55 ~ 64岁= 0.71,65 ~ 74岁= 0.98,75 ~ 84岁= 2.04,85岁以下= 0.74。结论:尼日利亚城市脑卒中患病率低于大多数发达国家。较低的发病率可能与发展中国家较低的发病率和较高的中风死亡率有关。版权所有(c) 2007 S. Karger AG,巴塞尔
Background: The burden of cerebrovascular disease in developing countries is projected to be on the rise. However, data on the current epidemiology of stroke in Africa are sparse. Methods: Using a 3-staged method, we conducted a door-to-door study of stroke in an urban, mixed-income community in Lagos, Nigeria. We used a modification of the WHO protocol in the first stage, a stroke-specific questionnaire in the second stage and neurological examination of all persons screening positive for stroke in the third stage. We also examined an equal number of stroke-negative persons. Results: Overall, the crude prevalence rate of stroke in urban Nigeria was 1.14/1,000 ( males: 1.51; females: 0.69). The age-adjusted prevalence rates per 1,000 ( adjusted to the USA population 2000) in mid-decade strata showed a trend of increasing prevalence with advancing age as follows: 35-44 years = 0.009, 45-54 years = 0.33, 55-64 years = 0.71, 65-74 years = 0.98, 75-84 years = 2.04 and > 85 years = 0.74. Conclusions: Stroke prevalence rates in urban Nigeria are lower than those in most developed countries. The lower rates may be related to lower incidence and higher stroke mortality in developing countries. Copyright (c) 2007 S. Karger AG, Basel