Lipase-catalyzed enantioselective acylation in the ionic liquid solvent system: Reaction of enzyme anchored to the solvent
Lipase-catalyzed enantioselective acylation in the ionic liquid solvent system: Reaction of enzyme anchored to the solvent
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DOI：
10.1246/cl.2001.262
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发表时间：
2001-03-05
影响因子：
1.6
通讯作者：
Shirakami, S
中科院分区：
文献类型：
--
作者：
Itoh, T;Akasaki, E;Shirakami, S
证明了离子液体溶剂中脂肪酶催化烯丙醇的对映选择性酰化反应：该反应显着依赖于咪唑鎓盐的抗衡阴离子，并且当反应在[bmim]PF6或[bmim]BF4作为溶剂中进行时获得了良好的结果。我们还首先证明了可以在离子液体溶剂系统中重复使用酶。
The lipase-catalyzed enantioselective acylation of allylic alcohols in an ionic liquid solvent was demonstrated: the reaction was significantly dependent on the counter anion of the imidazolium salt and good results were obtained when the reaction was carried out in [bmim]PF6 or [bmim]BF4 as solvent. We also first demonstrated that it was possible to repeatedly use the enzyme in the ionic liquid solvent system.