T-cell regulation: Thy-1-hiding in full view

T-cell regulation: Thy-1-hiding in full view
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DOI:
10.1016/s0960-9822(06)00402-7
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发表时间:
1997-12-01
期刊:
影响因子:
9.2
通讯作者:
Killeen, N
Killeen, N
中科院分区:
生物学1区
文献类型:
--
作者:
Killeen, N

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Thy-1是胸腺细胞和神经元表面高度丰富的糖蛋白,编码Thy-1的基因的无效突变会失调T细胞受体信号传导并导致胸腺细胞发育异常;这是否意味着Thy-1具有信号传导功能?
Thy-1 is a highly abundant glycoprotein on the surface of thymocytes and neurons, A null mutation in the gene encoding Thy-1 deregulates T-cell receptor signaling and causes abnormal thymocyte development; does this mean that Thy-1 has a signaling function?