Visible-Light-Induced C−H Functionalization and C−C/C−X Bond-Forming Oxidative Cross-Coupling Reactions
Visible-Light-Induced C−H Functionalization and C−C/C−X Bond-Forming Oxidative Cross-Coupling Reactions
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DOI：
10.1002/ajoc.201800214
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发表时间：
2018-06
影响因子：
2.7
通讯作者：
Heng Zhang;A. Lei
中科院分区：
文献类型：
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作者：
Heng Zhang;A. Lei
过渡金属催化的C - H功能化是近十年来有机化学研究的热点。光催化和C−H功能化的融合无疑是解决这一领域挑战的一个很有前途的策略，因为光诱导电子转移是激活C−H键的另一种途径。有机光氧化还原催化剂除了具有反应条件温和、位点选择性好等共同优点外，还具有没有潜在的过渡金属污染、价格低、候选物多、反应活性高等优点。在这篇重点综述中，我们集中研究了有机光氧化还原催化剂氧化交叉偶联的成键反应。综述了近年来在C−C和C−X （N， O， F， P， S, Cl, or Br）成键反应方面取得的进展。
Transition‐metal‐catalyzed C−H functionalization has been a hot topic in organic chemistry over the past decade. The convergence of photocatalysis and C−H functionalization is undoubtedly a promising strategy to solve the challenges in this area as photoinduced electron transfer represents another avenue for the activation of C−H bonds. In addition to the common merits of mild reaction conditions and good site selectivity, organic photoredox catalysts are superior to the transition metal photocatalysts (predominantly Ru‐ and Ir‐based polypyridyl complexes) in the following aspects: no potential transition metal contamination, low price, more candidates, and higher reactivity, and so forth. In this Focus Review, we concentrate on bond‐forming reactions by oxidative cross‐coupling using organic photoredox catalysts. Achievements on C−C and C−X (N, O, F, P, S, Cl, or Br) bond‐forming reactions made in recent years are summarized.