L2L: a simple tool for discovering the hidden significance in microarray expression data

L2L: a simple tool for discovering the hidden significance in microarray expression data
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DOI:
10.1186/gb-2005-6-9-r81
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发表时间:
2005-01-01
期刊:
影响因子:
12.3
通讯作者:
Weiner, AM
Weiner, AM
中科院分区:
生物学1区
文献类型:
--
作者:
Newman, JC;Weiner, AM

文献摘要

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L2L是一个数据库,由从已发表的哺乳动物微阵列研究中汇编的差异表达基因列表组成,同时还配有一个易于使用的应用程序,可用于使用用户自己的微阵列数据挖掘该数据库。正如对一项近期糖尿病肾病研究的重新分析所表明的那样,L2L能识别微阵列数据中的新型生物学模式,为了解生物学过程和疾病的潜在本质提供见解。L2L可在作者的网站[http://depts.washington.edu/l2l/]上在线获取。
L2L is a database consisting of lists of differentially expressed genes compiled from published mammalian microarray studies, along with an easy-to-use application for mining the database with the user's own microarray data. As illustrated by re-analysis of a recent study of diabetic nephropathy, L2L identifies novel biological patterns in microarray data, providing insights into the underlying nature of biological processes and disease. L2L is available online at the authors' website [http://depts.washington.edu/l2l/].