Sleep-associated augmentation and synchronization of luteinizing hormone pulses in adult men.
Sleep-associated augmentation and synchronization of luteinizing hormone pulses in adult men.
复制标题
成年男性中与睡眠相关的黄体生成激素脉冲的增强和同步。
DOI：
10.1159/000125875
复制
发表时间：
1991
影响因子：
4.1
通讯作者：
J. Born
中科院分区：
文献类型：
--
作者：
Lorenz Fehm;Jens Clausing;W. Kern;Reinhard Pietrowsky;J. Born
We reinvestigated the temporal relationship between sleep and LH secretion in healthy adult males by comparing LH secretion patterns during sleep with those during the 6 h of wakefulness preceding the sleep epoch. Sleep stages were determined by somnopolygraphy. In these subjects LH secretion was augmented during sleep as indicated by increased mean LH concentrations and increased pulse amplitudes; pulse frequency was not different. In addition, LH secretion appeared to be synchronized to the NonREM-REM sleep cycles: initiation of LH pulses occurred preferentially in the mid-portion of a NonREM-REM cycle during Non-REM sleep. Thus, REM sleep was almost uniformly associated with decreasing LH concentration. These findings demonstrate that patterns of LH secretion characteristic for early puberty are principally present also in adult males.
