Tuberculosis mortality associated with AIDS and drug or alcohol abuse: Analysis of multiple cause-of-death data

Tuberculosis mortality associated with AIDS and drug or alcohol abuse: Analysis of multiple cause-of-death data
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DOI:
10.1016/s0033-3506(96)80074-6
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发表时间:
1996-05-01
期刊:
影响因子:
5.2
通讯作者:
Portillo, CJ
Portillo, CJ
中科院分区:
医学3区
文献类型:
--
作者:
White, MC;Portillo, CJ

文献摘要

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20世纪80年代中期结核病发病率的回升增加了人们对结核病死亡率的兴趣。我们研究了美国1990年的结核病死亡率,使用多种死因数据来描述艾滋病和药物滥用(定义为药物或酒精滥用)对结核病死亡率的影响。按年龄分列的结核病死亡率呈双峰模式,峰值出现在25岁至55岁之间;按种族/族裔划分,黑人和西班牙裔男性的死亡率最高,黑人女性的死亡率接近西班牙裔男性。虽然在每个种族/族裔类别中,剔除艾滋病死亡导致的死亡曲线更接近1980年的死亡曲线,但黑人和西班牙裔的死亡仍然是双峰模式。当我们检查结核病和药物滥用的死亡时,我们发现,没有艾滋病的药物滥用可能是导致双峰模式的额外死亡原因。
The resurgence in tuberculosis morbidity in the mid-1980s has increased interest in tuberculosis mortality. We examined mortality in the United States, from tuberculosis in 1990, using multiple cause-of-death data to describe the impact of AIDS and substance abuse, defined as drug or alcohol abuse, on mortality from tuberculosis. Tuberculosis mortality by age showed a bimodal pattern, with a peak between ages 25 and 55; by race/ethnicity, black and Hispanic males had the highest mortality rates, and black females had rates close to those of Hispanic males. Although in each of the race/ethnicity categories the removal of deaths with AIDS resulted in mortality curves closer to those of 1980, the bimodal pattern remained for black and Hispanic deaths. When we examined deaths with tuberculosis and substance abuse, We found that substance abuse without AIDS may account for additional deaths contributing to the bimodal pattern seen.