Natural variation in the response of Caenorhabditis elegans towards Bacillus thuringiensis
Natural variation in the response of Caenorhabditis elegans towards Bacillus thuringiensis
复制标题
DOI：
10.1017/s003118200300461x
复制
发表时间：
2004-04-01
期刊：
影响因子：
2.4
通讯作者：
Müller, S
中科院分区：
文献类型：
--
作者：
Schulenburg, H;Müller, S
关于秀丽隐杆线虫的自然生态学，包括它与寄生虫的相互作用，几乎一无所知。为了帮助纠正这种差异，我们评估了C。一种潜在的寄生虫，土壤细菌苏云金芽孢杆菌。结果表明，来自世界各地的10个分离株在面对B的寄生株时，存活率和感染水平存在显著差异。苏云金杆菌。此外，行为反应被确定为C的一个重要组成部分。elegans防御，诱导逃避和可能减少寄生虫的摄入。同样，天然分离株在这些性状上显示出显着差异。总之，蠕虫的防御是复杂的，多变的空间，这意味着寄生虫在生态中发挥着重要作用，这个物种。基于这些结果，我们预期C.线虫是一个有前途的模式主机为未来的寄生虫-宿主相互作用的进化动力学分析。
Almost nothing is known about the natural ecology of the nematode Caenorhabditis elegans, including its interactions with parasites. To help rectify this discrepancy, we assessed natural variation in the response of C. elegans towards a potential parasite, the soil bacterium Bacillus thuringiensis. Our results show that 10 isolates from across the world differ significantly in survival rate and infection level when Confronted with a parasitic strain of B. thuringiensis. Furthermore, behavioural responses are identified as an important component of C. elegans defence, inducing evasion and possibly reduced ingestion of parasites. Again, the natural isolates show significant differences in these traits. In conclusion, worm defence is indicated to be complex and variable across space, implying that parasites play an important role in the ecology, of this species. Based on these results, we expect C. elegans to be a promising model host for future analysis of the evolutionary dynamics of parasite-host interactions.