Detecting Molecular Fingerprints in Single Molecule Force Spectroscopy Using Pattern Recognition
Detecting Molecular Fingerprints in Single Molecule Force Spectroscopy Using Pattern Recognition
复制标题
使用模式识别在单分子力谱中检测分子指纹
DOI:
10.1143/jjap.46.5540
复制
发表时间:
2007
影响因子:
1.5
通讯作者:
M. Rief
中科院分区:
文献类型:
--
作者:
Hendrik Dietz;M. Rief
Single molecule force spectroscopy has given experimental access to the mechanical properties of protein molecules. Typically, less than 1% of the experimental recordings reflect true single molecule events due to abundant surface and multiple-molecule interactions. A key issue in single molecule force spectroscopy is thus to identify the characteristic mechanical “fingerprint” of a specific protein in noisy data sets. Here, we present an objective pattern recognition algorithm that is able to identify fingerprints in such noisy data sets.
DOI:
10.1073/pnas.97.1.139
发表时间:
2000-01-04
影响因子:
11.1
作者:
Yang, GL;Cecconi, C;Bustamante, C
通讯作者:
Bustamante, C