Circuit dynamics of adaptive and maladaptive behaviour.
Circuit dynamics of adaptive and maladaptive behaviour.
复制标题
作者：
最近用于研究完整生物系统的特定组成部分的技术的发展使人们能够阐明适应和不适应行为背后的神经回路。研究人员现在能够以高时空分辨率观察和控制在复杂行为表现期间和之后电活动沿其流动的结构上定义的完整路径。这些研究表明，对投射特定动力学的控制非常适合于调节与广泛的精神疾病相关的行为模式。结构动力学原理已经出现，为完整和患病神经系统的运作提供了不同的、意想不到的和因果的见解，将大脑中的形式和功能联系起来。
The recent development of technologies for investigating specific components of intact biological systems has allowed elucidation of the neural circuitry underlying adaptive and maladaptive behaviours. Investigators are now able to observe and control, with high spatio-temporal resolution, structurally defined intact pathways along which electrical activity flows during and after the performance of complex behaviours. These investigations have revealed that control of projection-specific dynamics is well suited to modulating behavioural patterns that are relevant to a broad range of psychiatric diseases. Structural dynamics principles have emerged to provide diverse, unexpected and causal insights into the operation of intact and diseased nervous systems, linking form and function in the brain.