Evolutionary traction: the cost of adaptation and the evolution of sex
Evolutionary traction: the cost of adaptation and the evolution of sex
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DOI：
10.1111/j.1420-9101.2004.00858.x
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发表时间：
2005-03-01
影响因子：
2.1
通讯作者：
Feldman, MW
中科院分区：
文献类型：
--
作者：
Hadany, L;Feldman, MW
有性生殖的优势仍然是进化生物学家的一个难题。在其他条件相同的情况下，无性繁殖的种群所产生的后代数量预计将是相似的有性繁殖种群所产生的后代数量的两倍。然而，无性繁殖的物种在高等真核生物中并不常见。在假设小种群、高突变率或频繁环境变化的模型中，有性生殖似乎比无性生殖至少有两倍的优势。但是，性别对于大种群、低突变率和罕见或温和的环境变化的优势仍然是一个难题。在这里，我们表明，如果没有重组，罕见的有利突变可能会导致有害突变的积累增加（“进化牵引”），这解释了性别在很宽的参数范围内的长期优势。
The advantage of sexual reproduction remains a puzzle for evolutionary biologists. Everything else being equal, asexual populations are expected to have twice the number of offspring produced by similar sexual populations. Yet, asexual species are uncommon among higher eukaryotes. In models assuming small populations, high mutation rates, or frequent environmental changes, sexual reproduction seems to have at least a two-fold advantage over asexuality. But the advantage of sex for large populations, low mutation rates, and rare or mild environmental changes remains a conundrum. Here we show that without recombination, rare advantageous mutations can result in increased accumulation of deleterious mutations ('evolutionary traction'), which explains the long-term advantage of sex under a wide parameter range.