Risk-Sensitive Decision-Making Deficit in Adolescent Suicide Attempters
Risk-Sensitive Decision-Making Deficit in Adolescent Suicide Attempters
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DOI：
10.1089/cap.2014.0041
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发表时间：
2015-03-01
影响因子：
1.9
通讯作者：
Bridge, Jeffrey A.
中科院分区：
文献类型：
--
作者：
Ackerman, John P.;McBee-Strayer, Sandy M.;Bridge, Jeffrey A.
目的：青少年自杀是一个主要的公共卫生问题。决策缺陷可能在自杀行为的脆弱性中发挥重要作用，但很少有研究检查有自杀风险的青少年的决策表现。在这项研究中，我们试图延长最近的研究结果，青少年自杀budgeters过程中的风险评估不同于青少年谁没有企图suiction.Methods：我们评估了14个青少年自杀budgeters和14个非budgeter比较科目，年龄15-19岁，使用剑桥赌博任务（CGT）的决策。每位参与者还接受了诊断性访谈（Mini-International Neuropsychiatric Interview [MINI]）、结构化自杀严重程度测量和简要智商（IQ）测量。在控制了性别和智商差异后，自杀者在CGT上显示出比对照组更高的冒险倾向，因此他们更愿意用他们的积分银行冒更大的风险，这种决策风格随着时间的推移而被证明是不利的。没有组间差异的延迟或准确性的决策observed.Conclusions：青少年与自杀未遂的历史显示增加的风险承担和更大的困难预测可能的结果CGT。这种缺陷与眶额前额叶皮质功能障碍有关，这支持了其他研究，这些研究表明有自杀企图史的个体的决策能力受损。
Objective: Suicide among adolescents is a major public health problem. Decision-making deficits may play an important role in vulnerability to suicidal behavior, but few studies have examined decision-making performance in youth at risk for suicide. In this study, we seek to extend recent findings that adolescent suicide attempters process risk evaluations differently than adolescents who have not attempted suicide.Methods: We assessed decision-making in 14 adolescent suicide attempters and 14 non-attempter comparison subjects, ages 15-19, using the Cambridge Gambling Task (CGT). Each participant was also administered a diagnostic interview (Mini-International Neuropsychiatric Interview [MINI]), structured suicide severity measures, and a brief intelligence quotient (IQ) measure.Results: After controlling for gender and IQ differences, suicide attempters displayed an elevated risk-taking propensity on the CGT relative to comparison subjects, such that they were more willing to take a large risk with their bank of points, a decision-making style that proves disadvantageous over time. No group differences in the latency or accuracy of decision-making were observed.Conclusions: Adolescents with a history of suicide attempt display increased risk-taking and greater difficulty predicting probable outcomes on the CGT. Such deficits have been associated with dysfunction in the orbitofrontal prefrontal cortex, which supports other studies implicating impaired decision-making among individuals with a history of suicide attempt.