Fibroelastolytic papulosis of the neck: a report of 20 cases
Fibroelastolytic papulosis of the neck: a report of 20 cases
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DOI：
10.1046/j.1365-2133.1997.18711957.x
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发表时间：
1997-09-01
影响因子：
10.3
通讯作者：
Bellocci, M
中科院分区：
文献类型：
--
作者：
Balus, L;Amantea, A;Bellocci, M
被称为“颈部白色纤维丘疹病”(WFPN)和“似弹性假黄瘤的获得性乳头状真皮弹性溶解”(PDE)的实体的临床和组织学特征尚不清楚。这项研究是为了将我们的WFPN/PDE的经验与文献中所描述的进行比较。20名患者出现在我们的机构，丘疹皮疹累及颈部。无症状的皮损，从正常肤色到淡黄色不等，是孤立的或合并的。显微镜下，丘疹表现为上网状真皮和乳头状真皮的弹性溶解和纤维化，回顾文献，在报道为WFPN和PDE的病例中显示出类似的特征。这项研究表明，WFPN和PDE是一种单一疾病的变种，可以更准确地定义为“颈部纤维弹性增殖性丘疹病”，似乎是皮肤固有老化的表现。
The clinical and histological features of the entities known as 'white fibrous papulosis of the neck' (WFPN) and 'acquired elastolysis of the papillary dermis simulating pseudoxanthoma elasticum' (PDE) are not clearly defined. This study was conducted to compare our experience of WFPN/PDE with those described in the literature. Twenty patients presented at our institution with papular eruptions involving the neck. The asymptomatic lesions, which ranged in colour from normal skin tones to yellowish, were isolated or coalescent. Microscopically, the papules showed elastolysis and fibrosis of the upper reticular and papillary dermis, A review of the literature shows similar characteristics in cases reported as WFPN and PDE. This study indicates that WFPN and PDE are variants of a single disorder that can be more precisely defined as 'fibroelastolytic papulosis of the neck' and which appears to be a manifestation of intrinsic skin ageing.