Antibiotic prescription for endodontic infections: a survey of Brazilian Endodontists

Antibiotic prescription for endodontic infections: a survey of Brazilian Endodontists
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DOI:
10.1111/iej.12823
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发表时间:
2018-02-01
影响因子:
5
通讯作者:
Jacinto, R. C.
Jacinto, R. C.
中科院分区:
医学2区
文献类型:
--
作者:
Bolfoni, M. R.;Pappen, F. G.;Jacinto, R. C.

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目的调查巴西牙髓医生在特定临床情况下的抗生素处方习惯。方法邀请巴西牙髓医生(n = 13853)填写在线问卷。问卷由两部分组成:第一部分包含年龄、性别、工作年限、牙髓诊疗地点等个人资料;第二部分包括他们在牙科诊所开抗生素处方时的行为问题。受试者提供了他们在区域牙科管理局(RCD)的注册编号,以防止数据重复。数据收集和分析采用SPSS 17.0 (SPSS, Inc., Chicago, IL, USA)。采用卡方检验和Fisher精确检验检验可能关联的显著性(P < 0.05)。结果13853份问卷中,回复率为615份(4.44%)。首选抗生素为阿莫西林(81.5%),其次为阿莫西林+克拉维酸(30.7%)。对于急性根尖脓肿伴口内外弥漫性肿胀、发热、牙关,90.1%的人会开抗生素,88.1%的人即使没有口外肿胀、发热、牙关也会开抗生素,20.5%的人会在慢性根尖牙周炎、窦道的情况下开抗生素。首选抗生素因牙医年龄(P < 0.001)和牙髓毕业时间(P = 0.001)而异。结论:许多牙髓医生报告在不需要抗生素的情况下开抗生素处方。同样,抗生素的一般管理持续时间比必要的更长,加强了对抗生素使用的持续教育的需要。
Aim To investigate antibiotic prescribing habits reported by Brazilian endodontists in specific clinical situations.Methodology Brazilian endodontists (n = 13 853) were invited to answer an online questionnaire. The questionnaire consisted of two parts: the first part contained personal data such as age, gender, years of experience and location of endodontic practice; the second part included questions regarding their behaviour when prescribing antibiotics in dental practice. The subjects provided their registration number in the Regional Council of Dentistry (RCD) to prevent duplication of data. Data were collected and analysed by SPSS 17.0 (SPSS, Inc., Chicago, IL, USA). Chi-square and Fisher's exact tests were used to test the significance of possible associations (P < 0.05).Results From the 13853 questionnaires, a total of 615 were answered (4.44%). The first-choice antibiotic was amoxicillin (81.5%), followed by amoxicillin+clavulanic acid (30.7%). For acute apical abscesses with intra- and extraoral diffuse swelling, fever and trismus, 90.1% reported they would prescribe antibiotics, whilst 88.1% reported they would prescribe antibiotics even without extraoral swelling, fever and trismus, and 20.5% would prescribe antibiotics in cases of chronic apical periodontitis, and sinus tract. The first-choice antibiotics varied by age of dentist (P < 0.001) and time elapsed since their endodontic graduation (P = 0.001).Conclusions Many endodontists reported prescribing antibiotics insituations where they would not be indicated. Likewise, the general administration of antibiotics was longer in duration than necessary, reinforcing the need of continuous education regarding the use of antibiotics.