New hindered isomers of 3-dehydroretinal (vitamin A(2))
New hindered isomers of 3-dehydroretinal (vitamin A(2))
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DOI：
10.1016/0040-4020(96)00355-9
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发表时间：
1996-06-03
期刊：
影响因子：
2.1
通讯作者：
Liu, RSH
中科院分区：
文献类型：
--
作者：
Chen, RL;Liu, RSH
3-脱氢视网膜（1，维生素A(2)） 6个新异构体（7-顺、7,9-二、7,11-二、7,13-二、7,9,11-三和7,9,13-三）的制备。并报道了它们的光谱性质。由于在脱氢系列中较小的构建块的光敏异构化过程中意想不到的1,7- h迁移，在3-脱氢视网膜的新阻碍异构体的合成中引入7-顺式几何结构需要在3,4-双键之前构建这个顺式双键。版权所有爱思唯尔科学有限公司
The preparation of six new isomers (7-cis, 7,9-dicis, 7,11-dicis, 7,13-dicis, 7,9,11-tricis and 7,9,13-tricis) of 3-dehydroretinal (1, vitamin A(2)). and their spectroscopic properties are reported. Because of the unexpected 1,7-H migration in photo-sensitized isomerization of the smaller building blocks in the dehydro-series, the introduction of the 7-cis geometry in the synthesis of new hindered isomers of 3-dehydroretinal required construction of this cis-double bond prior to that of the 3,4-double bond. Copyright (C) 1996 Elsevier Science Ltd