Echocardiographic assessment of cardiovascular hemodynamics in normal pregnancy
Echocardiographic assessment of cardiovascular hemodynamics in normal pregnancy
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DOI：
10.1097/01.aog.0000128170.15161.1d
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发表时间：
2004-07-01
影响因子：
7.2
通讯作者：
Naidoo, DP
中科院分区：
文献类型：
--
作者：
Desai, DK;Moodley, J;Naidoo, DP
目的：影响正常妊娠心输出量的因素仍有争议。本研究通过超声心动图前瞻性地评价了健康孕妇在妊娠后半期的母体中心血流动力学和心脏结构与功能，以及母体身高校正和这些变量之间的相关性。方法：对35例健康孕妇进行了160项超声心动图研究，从妊娠早期至足月和产后6-12周进行纵向评价。心输出量在妊娠早期至中期显著增加，并维持至足月。它主要在妊娠后半期增加，46-51%的峰值心输出量发生在心率增加15%和每搏输出量增加24%。孕晚期早期测量的母体心输出量与母体体表面积（r = 0.72; P <0.001）和胎儿出生体重（r = 0.52; P = 0.008）有良好的相关性。左心室收缩功能一直保持到足月。结论：母体心输出量在孕晚期早期至中期达到峰值，并一直维持到足月。孕妇心输出量、孕妇体表面积和胎儿出生体重之间存在显著相关性。(C)2004年由美国妇产科医师学会。
OBJECTIVE: The factors affecting cardiac output in normal pregnancy remain controversial. This study prospectively evaluates maternal central hemodynamics and cardiac structure and function by echocardiography, together with maternal stature correction and correlation of these variables in healthy pregnant women in the latter half of pregnancy.METHODS: One hundred sixty echocardiographic studies were performed in 35 healthy pregnant women for longitudinal evaluation from early second trimester until term and 6-12 weeks postpartum.RESULTS: Cardiac output increased significantly at the early to mid third trimester and was maintained until term. It increased predominantly in the latter half of pregnancy, and peak cardiac output of 46-51% occurred from a 15% increase in heart rate and 24% increase in stroke volume. Maternal cardiac output measured in the early third trimester showed a good correlation with maternal body surface area (r = 0.72; P < .001) and fetal birth weight (r = 0.52; P = .008). Left ventricular systolic function was preserved until term.CONCLUSION: Maternal cardiac output peaks in the early to mid third trimester and is maintained until term. Significant correlations were observed among maternal cardiac output, maternal body surface area, and fetal birth weight. (C) 2004 by The American College of Obstetricians and Gynecologists.