Structure Validation of Complex Natural Products: Time to Change the Paradigm. What did Synthesis of Alstofolinine A Prove?
Structure Validation of Complex Natural Products: Time to Change the Paradigm. What did Synthesis of Alstofolinine A Prove?
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DOI：
10.1021/acs.joc.9b00969
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发表时间：
2019-06-21
影响因子：
3.6
通讯作者：
Holt, Tina
中科院分区：
文献类型：
--
作者：
Kutateladze, Andrei G.;Holt, Tina
全合成已成为复杂天然产物结构验证（或修正）的一种有效且广泛实践的方法。结构解析的计算方法似乎正逐渐成为一种更好的选择，更快，更可靠，如alstooflinine a的情况。
Total synthesis has been an effective and broadly practiced approach for structure validation (or revision) of complex natural products. It appears that computational methods for structure elucidation are gradually becoming a better alternative, being faster and more reliable, as found in the case of alstofolinine A.