Sources of opioid medication for misuse in older adults: results from a nationally representative survey.
Sources of opioid medication for misuse in older adults: results from a nationally representative survey.
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DOI：
10.1097/j.pain.0000000000001241
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发表时间：
2018-08
期刊：
影响因子：
7.4
通讯作者：
Teter CJ
中科院分区：
文献类型：
--
作者：
Schepis TS;McCabe SE;Teter CJ
尽管50岁及以上的成年人滥用处方阿片类药物(PO)的比率不断上升，但很少有研究调查这一人群中的这种滥用情况。这项工作旨在检查50岁及以上成年人滥用阿片类药物的来源，并与年轻群体进行比较。数据来自2009年至2014年全国毒品使用和健康调查。评估PO来源、滥用和PO使用障碍(POUD)症状的患病率。基于设计的Logistic回归研究了这些因素基于年龄的差异，以及来源与POUD症状和其他同时使用物质的关系。在65岁及以上的成年人中，近一半(47.7%)的人在过去30天内滥用医生来源的PO，其中50岁至年龄段的比例第二高(39.2%)。相反，利用盗窃(5.3%)、购买(8.5%)或朋友/家人(免费；23.2%)获得阿片类药物在65岁及以上的成年人中最不常见，这些来源的流行率在50岁及以上人群中更接近年轻群体。在这50岁及以上的人群中，购买、医生或多种来源的使用与POUD症状患病率的升高有关。老年人，特别是65岁及以上的老年人，使用不同于青少年或年轻人的PO来源模式，而那些使用医生来源的人POUD症状增加。医生是老年人获得阿片类药物滥用的关键途径，这突显了临床医生在限制这种滥用方面的潜在作用。
Despite increasing rates of prescription opioid (PO) misuse in adults 50 years of age and older, little research has investigated such misuse in this population. This work aimed to examine sources of misused opioid medication in adults 50 years and older, with comparisons to younger groups. Data were from the 2009 to 2014 National Survey on Drug Use and Health surveys. Prevalence rates of PO sources, misuse, and PO use disorder (POUD) symptoms were estimated. Design-based logistic regression investigated age-based differences in these factors and the association of sources with POUD symptoms and other concurrent substance use. Nearly half (47.7%) of adults 65 years and older used physician sources for past 30-day PO misuse, with the second highest rates in those 50 to 64 years old (39.2%). Conversely, use of theft (5.3%), purchases (8.5%), or friends/family (for free; 23.2%) to obtain opioids were least common in adults 65 years and older, with prevalence rates of these sources in those 50 years and older closer to those of younger groups. Across those 50 years and older, use of purchases, physician, or multiple sources were associated with elevated POUD symptom prevalence. Older adults, particularly those 65 years and older, use a different pattern of PO sources than adolescents or younger adults, and those using physician sources have elevated POUD symptoms. Physicians are a key avenue for older adults to obtain opioids for misuse, highlighting the potential role of clinicians in limiting such misuse.
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影响因子：
4.4
作者：
McCabe, SE;Boyd, CJ
通讯作者：
Boyd, CJ
CDC规定慢性疼痛的阿片类药物的指南 - 美国，2016年。
DOI：
10.1001/jama.2016.1464
发表时间：
2016-04-19
期刊：
JAMA
影响因子：
--
作者：
Dowell D;Haegerich TM;Chou R
通讯作者：
Chou R
影响因子：
5.3
作者：
McCabe, Sean Esteban;Teter, Christian J.;Schepis, Ty S.
通讯作者：
Schepis, Ty S.
影响因子：
17.7
作者：
Compton, Wilson M.;Dawson, Deborah A.;Grant, Bridget F.
通讯作者：
Grant, Bridget F.
影响因子：
25.8
作者：
Olfson, Mark;King, Marissa;Schoenbaum, Michael
通讯作者：
Schoenbaum, Michael