Prevalence of Corneal Astigmatism and Anterior Segmental Biometry Characteristics Before Surgery in Chinese Congenital Cataract Patients.
Prevalence of Corneal Astigmatism and Anterior Segmental Biometry Characteristics Before Surgery in Chinese Congenital Cataract Patients.
复制标题
中国先天性白内障患者术前角膜散光患病率及眼前节生物测量特征
DOI：
10.1038/srep22092
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发表时间：
2016-02-25
影响因子：
4.6
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Lin D;Chen J;Liu Z;Wu X;Long E;Luo L;Lin Z;Li X;Zhang L;Chen H;Liu J;Chen W;Lin H;Liu Y
中国先天性白内障患者术前角膜散光和眼前节生物测量的患病率和分布特征尚不完全清楚。本研究纳入了2011年2月至2015年8月从中山眼科中心入组的400例CC患者。用Pentacam Scheimpflug系统测量CA、角膜曲率、中央角膜厚度（CCT）和前房深度（ACD）。患者平均年龄为54.27个月，男女之比为1.53：1。平均CA为2.03屈光度（D），39.25%的受试者的CA值≥2 D。最常见（71.8%）的诊断是规则散光。16.2%的病例存在斜散光，12%的病例存在逆规则散光。双侧白内障患者的角膜曲率平均值明显大于单侧白内障患者。女孩有一个较大的平均角膜曲率，但薄CCT比男孩。单侧患者白内障眼的CA、CCT和ACD显著大于非白内障眼。CC患者的CA、平均角膜曲率、CCT和ACD随年龄、性别和偏侧性而变化。充分了解这些特征可能有助于为CC患者的指南和治疗决策提供信息。
The prevalence and the distribution characteristics of corneal astigmatism (CA) and anterior segment biometry before surgery in Chinese congenital cataract (CC) patients are not completely understood. This study involved 400 CC patients from the Zhongshan Ophthalmic Center enrolled from February 2011 to August 2015. Data on CA, keratometry, central corneal thickness (CCT) and anterior chamber depth (ACD) were measured by the Pentacam Scheimpflug System. The mean age of patients was 54.27 months, and the ratio of boys to girls was 1.53:1. The mean CA was 2.03 diopters (D), and 39.25% of subjects had CA values ≥2 D. The most frequent (71.8%) diagnosis was with-the-rule astigmatism. Oblique astigmatism was present in 16.2% of cases, and 12% of cases had against-the-rule astigmatism. The mean keratometry measurement of cataractous eyes in bilateral patients was significantly larger than that in unilateral patients. Girls had a larger mean keratometry but a thinner CCT than did boys. The CA, CCT, and ACD of cataractous eyes were significantly larger than those of non-cataractous eyes in unilateral patients. The CA, mean keratometry, CCT, and ACD in CC patients varied with age, gender, and laterality. Fully understanding these characteristics may help inform guidelines and treatment decisions in CC patients.