The Nature of Dandruff

The Nature of Dandruff
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头皮屑的本质

DOI:
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发表时间:
1976
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影响因子:
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通讯作者:
James J. Lmq
James J. Lmq
中科院分区:
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文献类型:
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作者:
Rt M. KLICMaN;James J. Lmq

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电影:对某个问题的兴趣与其流行程度的平方成反比。罕见疾病引起了人们极大的兴趣;伟大的思想和金钱被投入到他们的研究中。相反,熟悉的事物会受到蔑视和忽视。头皮屑还说明了治疗进步的不利影响:当控制手段被开发出来时,好奇心就会崩溃。抑制疾病的力量削弱了对其内在品质的兴趣。长期以来引起我们关注的两条研究路径,即皮肤微生物学和角质层,最终将我们引向了头皮。近十年来,我们一直在认真研究头皮屑。我们写这篇文章的目的是讲述我们所学到的知识,并根据我们的个人经历来概述头皮屑。在这里,我们不太关心原始数据,而是关心什么是头皮屑及其行为方式。 I. 定义 头皮屑是临床上过度的头皮非炎症性鳞屑。在大多数情况下,只需检查和刮擦表面即可几乎立即做出诊断。身体其他部位的病变需要注意也涉及头皮的疾病,特别是脂溢性皮炎和牛皮癣。当后者主要局限于头皮时,就会出现困难,因为炎症变化被掩盖在这个位置。头皮皮肤很厚,发红和渗出物可能被层层鳞屑所掩盖。缩放本身是一个非常非特异性的标志。需要丰富的经验来识别不同皮肤病的特殊形态特征,即牛皮癣的银色鳞屑或脂溢性皮炎的油腻鳞屑。我们总是询问过去和现在的皮肤病。错误的诊断虽然并不常见,但足够频繁地造成一些危害。令人不安的是,我们经常将另一种过程误认为是头皮屑,最常见的是老年受试者的脂溢性皮炎。诊断仪
cine: interest in a problem is inversely proportional to the square of its prevalence. Rare disorders evoke great interest; great minds and monies are applied to their study. Conversely, familiar things are scorned and neglected. Dandruff also illustrates an adverse effect of therapeutic advances: curiosity collapses when a means of control is developed. The power to subdue a disorder weakens interest in its inner qualities. Two paths of investigation, which have long occupied our attention, namely, CUTANEOUS MICROBIOLOGY and the HORNY LAYER, finally led us to the SCALP. We have been serious students of dandruff for almost a decade. It is our intent in this paper to tell what we have learned and to present an overview of dandruff in the light of our personal experience. We shall be less concerned here with raw data than with ideas of what dandruff is and how it behaves. I. DEFINITION Dandruff is excessive clinically noninflammatory scaling of the scalp. In the great majority of cases, diagnosis can be made almost instantly by simply inspecting and scratching the surface. Lesions elsewhere on the body call attention to disorders which also happen to involve the scalp, notably seborrheic dermatitis and psoriasis. Difilculties arise when the latter are chiefly confined to the scalp for inflammatory changes are masked in this location. Scalp skin is thick and redness and exudation may be hidden by layers of scale. Scaling itself is a very nonspecific sign. Great experience is needed to recognize the special morphologic qualities of different dermatoses, viz., the silvery scale of psoriasis or the greasy scale of seborrheic dermatitis. We always inquire about past and present skin disease. Wrong diagnoses, while not common, are frequent enough to cause some mischief. It is disquieting how often we have mistaken another process for dandruff, most often seborrheic dermatitis in older subjects. Diagnostic er