Tamoxifen Prophylaxis: Prevention is Better Than Cure — Prevention is Cure?
Tamoxifen Prophylaxis: Prevention is Better Than Cure — Prevention is Cure?
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他莫昔芬预防：预防胜于治疗——预防就是治疗？
DOI：
10.1007/978-3-642-71506-8_9
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发表时间：
1986
影响因子：
3.6
通讯作者：
V. Jordan
中科院分区：
文献类型：
--
作者：
V. Jordan
晚期乳腺癌的治疗与手术，激素的方式，放疗和化疗遇到了姑息治疗，在面对无意识的进展性疾病。在睾丸癌、霍奇金病或儿童白血病中观察到的化疗的显著成功很少在晚期乳腺癌中观察到。取得的成就往往是有代价的。在严格的化疗方案中，不适和副作用是患者经常的伴侣。不幸的是，客观和全面的反应总是转向迅速增长的耐药和耐辐射疾病。
The treatment of advanced breast cancer with surgery, hormonal modalities, radiotherapy and chemotherapy has met with palliation in the face of relentlessy progressive disease. The remarkable successes observed with chemotherapy in testicular carcinoma, Hodgkin’s disease or childhood leukaemias are rarely, if ever, observed in advanced breast cancer. Often the gains made are at a price. Discomfort and side effects are the patients’ constant companions during rigorous chemotherapy regimens. Unfortunately, objective and complete responses invariably turn to rapidly growing drug-and radiation-resistant disease.