A theory of the influence of eye movements on the refinement of direction selectivity in the cat's primary visual cortex.
A theory of the influence of eye movements on the refinement of direction selectivity in the cat's primary visual cortex.
复制标题
眼球运动对猫初级视觉皮层方向选择性细化影响的理论。
DOI：
10.3109/09548980903314204
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发表时间：
2009
影响因子：
7.8
通讯作者：
Rucci, Michele
中科院分区：
文献类型：
--
作者：
Casile, Antonino;Rucci, Michele
关键词：
在生命的早期，视觉经验影响初级视觉皮层神经元对特定刺激特征的优先反应的细化。这种影响的一个突出的例子是在高频频闪照明下饲养的猫中观察到的皮质方向选择性的减少。虽然已经提出了各种机制来解释神经元反应的个体特性的成熟，但皮层神经元的多个反应特征的联合发展的统一解释仍然是难以捉摸的。在这项研究中，我们表明，Hebbian突触可塑性帐户的同时完善的方向和方向选择性正常和频闪饲养，如果考虑到时空输入到视网膜在oculabular活动。在LGN和V1的计算模型中，眼球运动足以建立在暴露于自然刺激期间对方向和方向选择性反应进行赫布改进所需的丘脑皮质活动模式。此外，我们表明，考虑固定眼球运动解释了同时失去的方向选择性和保存的方向选择性观察到的结果频闪饲养。这些结果进一步支持了V1神经元的响应特性的细化中的oculabetin活动的作用。
Early in life, visual experience influences the refinement of the preferential response for specific stimulus features exhibited by neurons in the primary visual cortex. A striking example of this influence is the reduction in cortical direction selectivity observed in cats reared under high-frequency stroboscopic illumination. Although various mechanisms have been proposed to explain the maturation of individual properties of neuronal responses, a unified account of the joint development of the multiple response features of cortical neurons has remained elusive. In this study, we show that Hebbian synaptic plasticity accounts for the simultaneous refinement of orientation and direction selectivity under both normal and stroboscopic rearing, if one takes into account the spatiotemporal input to the retina during oculomotor activity. In a computational model of the LGN and V1, eye movements are sufficient to establish the patterns of thalamocortical activity required for a Hebbian refinement of both direction- and orientation selective responses during exposure to natural stimuli. Furthermore, we show that consideration of fixational eye movements explains the simultaneous loss of direction selectivity and preservation of orientation selectivity observed as a consequence of stroboscopic rearing. These results further support a role for oculomotor activity in the refinement of the response properties of V1 neurons.
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