Effects of a hepatitis C virus educational intervention or a motivational intervention on alcohol use, injection drug use, and sexual risk behaviors among injection drug users.
Effects of a hepatitis C virus educational intervention or a motivational intervention on alcohol use, injection drug use, and sexual risk behaviors among injection drug users.
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DOI：
10.2105/ajph.2007.126854
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发表时间：
2009-04
影响因子：
12.7
通讯作者：
Wechsberg WM
中科院分区：
文献类型：
--
作者：
Zule WA;Costenbader EC;Coomes CM;Wechsberg WM
Hepatitis C virus (HCV) is the most prevalent bloodborne infection in the United States, and alcohol use increases HCV progression. We compared the effects of two interventions on alcohol use, injection risk, and sexual risk in a community sample of injecting drug users. Eight hundred fifty-one out-of-treatment injecting drug users were recruited through street outreach and randomized to either a 6-session educational intervention or a 6-session motivational intervention. Intervention effects were examined at 6 and 12 months post enrollment. In multiple logistic regression analyses, adjusted for baseline alcohol use and HCV status, participants assigned to the motivational intervention were significantly less likely than participants in to be drinking at 6-month follow-up (odds ratio = 0.67, 95% confidence interval = 0.46, 0.97). There were no significant between group differences in injection risk or sexual risk at either follow-up. The motivational intervention was more effective than the educational intervention in reducing alcohol use at 6-month follow-up. Reducing alcohol use among people with HCV may slow disease progression and provide important health benefits.
