Noninvasive assessment of the digital volume pulse - Comparison with the peripheral pressure pulse
Noninvasive assessment of the digital volume pulse - Comparison with the peripheral pressure pulse
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DOI：
10.1161/01.hyp.36.6.952
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发表时间：
2000-12-01
期刊：
影响因子：
8.3
通讯作者：
Chowienczyk, PJ
中科院分区：
文献类型：
--
作者：
Millasseau, SC;Guigui, FG;Chowienczyk, PJ
用光体积描记法可以简单、无创地记录数字体积脉搏。本研究的目的是确定是否可以使用广义传递函数将数字体积脉冲与外周压力脉冲联系起来，从而确定体积和压力脉冲波形是否受相同机制的影响。60例受试者(女性10例，年龄24~80岁)，包括20例既往诊断为高血压的受试者，用光体积描记仪记录了数字容积脉搏。分别用压平眼压计和伺服控制压力袖带(Finapres)同步记录外周桡动脉脉搏和指动脉脉搏。在20名血压正常的受试者中，在舌下注射硝酸甘油(NTG，500杯)后进行测量。通过对波形进行傅立叶分析得到的传递函数在正常血压和高血压受试者中相似。在血压正常的受试者中，NTG前后的传递函数相似。通过对所有受试者使用单一的广义传递函数，从体积脉搏可以预测出桡动脉和指动脉的压力波形，其平均均方根误差分别为4.4+/-2.0和4.3+/-1.9 mm Hg(平均值+/-SD)，与两种压力波形之间的误差(4.4+/-1.4 mm Hg)相似。外周压力脉冲通过传递函数与数字体积脉冲相关，不受高血压或NTG的影响。NTG对体积脉搏和压力脉搏的影响可能由类似的机制决定。
The digital volume pulse can be recorded simply and noninvasively by photoplethysmography. The objective of the present study was to determine whether a generalized transfer function can be used to relate the digital volume pulse to the peripheral pressure pulse and, hence, to determine whether both volume and pressure pulse waveforms are influenced by the same mechanism. The digital volume pulse was recorded by photoplethysmography in 60 subjects (10 women, aged 24 to 80 years), including 20 subjects with previously diagnosed hypertension. Simultaneous recordings of the peripheral radial pulse and digital artery pulse were obtained by applanation tonometry and a servocontrolled pressure cuff (Finapres), respectively. In 20 normotensive subjects, measurements were obtained after the administration of nitroglycerin (NTG, 500 mug sublingually). Transfer functions obtained by Fourier analysis of the waveforms were similar in normotensive and hypertensive subjects. In normotensive subjects, transfer functions were similar before and after NTG. By use of a single generalized transfer function for all subjects, the radial and digital artery pressure waveforms could be predicted from the volume pulse with an average root mean square error of 4.4+/-2.0 and 4.3+/-1.9 mm Hg (mean+/-SD) for radial and digital artery waveforms, respectively, similar to the error between the 2 pressure waveforms (4.4+/-1.4 mm Hg). The peripheral pressure pulse is related to the digital volume pulse by a transfer function, which is not influenced by effects of hypertension or NTG. Effects of NTG on the volume pulse and pressure pulse are likely to be determined by a similar mechanism.