Influenza vaccination rate among patients with moderate to severe psoriasis

Influenza vaccination rate among patients with moderate to severe psoriasis
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DOI:
10.1111/ddg.12010
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发表时间:
2013-09-01
影响因子:
3.6
通讯作者:
Augustin, Matthias
Augustin, Matthias
中科院分区:
医学3区
文献类型:
--
作者:
Radtke, Marc Alexander;Rustenbach, Stephan Jeff;Augustin, Matthias

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背景慢性炎症性疾病如寻常型银屑病患者是流感病毒感染后发生严重并发症的高危人群。通过对这一群体进行疫苗接种,可以预防此类并发症。目的是确定中重度银屑病患者的疫苗接种率,并探讨周围的环境environments.Patients和方法在全国范围内,非干预性,横断面研究进行了1,229例确诊银屑病或银屑病关节炎的成年人。该调查包括15个关于疫苗接种和疫苗接种依从性的问题,分发给银屑病患者登记处PsoBest.Results约28%的患者(95%CI 24.0-31.6)接种疫苗。平均年龄为58岁,40%为女性。银屑病关节炎的患病率在基线时为28%,在疫苗接种期间为39%。全科医生对50%的患者进行了疫苗接种,而皮肤科医生建议对7%的病例进行疫苗接种。50%的患者报告说,他们是应自己的要求接种疫苗的。91%的患者在过去10年中至少接种过一次流感疫苗,平均接种5.9次。结论研究队列的疫苗接种率相对较低。只有一小部分医生建议接种流感疫苗。
Background Patients with chronic inflammatory diseases such as psoriasis vulgaris represent a risk group for developing serious complications after influenza virus infection. By vaccinating this cohort such complications might be prevented. The objective was to determine the vaccination rate among patients with moderate to severe psoriasis and to explore the surrounding circumstances.Patients and methods A nationwide, non-interventional, cross-sectional study was performed in 1,229 adults with confirmed psoriasis or psoriatic arthritis. The survey consisting of 15 questions about vaccination and vaccination adherence was distributed to patients enrolled in the psoriasis patient registry PsoBest.Results About 28 % of the patients (95 %-CI 24.0-31.6) were vaccinated. The mean age was 58 years, 40 % were females. The prevalence of psoriatic arthritis was 28 % at baseline and 39 % during the vaccination period. General practitioners vaccinated 50 % of the patients, while dermatologists suggested vaccination in 7 % of the cases. Fifty percent of the patients reported that they had been vaccinated at their own request. 91 % of the patients had been vaccinated at least once over the past ten years, receiving on average 5.9 influenza vaccinations during the decade.Conclusions The vaccination rate in the study cohort was relatively low compared to that in the general population. Influenza vaccination had only been suggested by a small percentage of physicians.