Scotoma mapping by semi-automated kinetic perimetry: the effects of stimulus properties and the speed of subjects' responses

Scotoma mapping by semi-automated kinetic perimetry: the effects of stimulus properties and the speed of subjects' responses
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DOI:
10.1111/j.1600-0420.2005.00624.x
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发表时间:
2006-06-01
期刊:
ACTA OPHTHALMOLOGICA SCANDINAVICA
影响因子:
--
通讯作者:
Hart, William
Hart, William
中科院分区:
其他
文献类型:
--
作者:
Dolderer, Jan;Vonthein, Reinhard;Hart, William

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目的:本研究的目的是首先确定的影响刺激变量上的暗点边界的检测,其次,研究的方法在半自动化的动态perimetry.Methods:生理盲点的大小在18名年轻的正常人进行了测量与视频campimetric设备,Tubingen计算机campimeter(TCC)的重复性。两种不同大小的动力学刺激,并在四个不同的亮度水平。在2周内重复检查。针对个体响应时间校正测量值,并计算盲点的面积。刺激强度和大小的影响和盲点测量的可重复性进行了评估,通过方差analysis of variance.Results:生理盲点表现出显着的个体间和个体内的变化的大小(最小二乘均值范围从17至49平方度),与6.8平方度的标准偏差。盲点的测量尺寸随着刺激值的减小而增加,通过减小相对亮度或刺激的尺寸。对每个受试者的反应速度进行校正,几乎使随机方差水平减半。测量的时间顺序(顺序,他们进行)没有明显的影响盲点size.Conclusions的计算值:半自动动态视野检查可以确定的生理盲点的大小,具有良好的可重复性,在年轻的,正常的科目。确定每个人的反应速度并将此变量纳入计算中,可显着降低测量的方差。这项研究证实了存在相当大的个体间差异的生理盲点的大小。
Purpose: The study aimed firstly to determine the effects of stimulus variables on the detection of a scotoma border and, secondly, to study the reproducibility of the method during semi-automated kinetic perimetry.Methods: The size of the physiological blind spot in 18 young normal subjects was measured with a video-campimetric device, the Tubingen computer campimeter (TCC). Kinetic stimuli of two different sizes and at four different levels of luminance were presented. Examinations were repeated within 2 weeks. Measurements were corrected for individual response times and the area of the blind spot was computed. The effects of stimulus strength and size and the repeatability of blind spot measurements were evaluated by an analysis of variance.Results: The physiological blind spot showed significant inter- and intraindividual variations in size (least square means ranging from 17 to 49 square degrees), with a standard deviation of 6.8 square degrees. The measured size of the blind spot increased as a function of decreasing stimulus value, by reducing either the relative brightness or the size of stimuli. Use of a correction for each subject's speed of responses nearly halved the level of random variance. The temporal sequence of measurements (the order in which they were performed) had no apparent effect on the calculated values of blind spot size.Conclusions: Semi-automated kinetic perimetry can determine the size of the physiological blind spot with good repeatability in young, normal subjects. Determination of each individual's speed of response and inclusion of this variable in the calculations reduced variance of the measure significantly. This study confirmed the presence of considerable interindividual differences in the size of the physiological blind spot.