COHERENCE BETWEEN FLUCTUATIONS IN BLOOD FLOW AND OXYGEN SATURATION

COHERENCE BETWEEN FLUCTUATIONS IN BLOOD FLOW AND OXYGEN SATURATION
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DOI:
10.1142/s0219477512400135
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发表时间:
2012-03-01
影响因子:
1.8
通讯作者:
Clarkson, Peter B. M.
Clarkson, Peter B. M.
中科院分区:
工程技术4区
文献类型:
--
作者:
Bernjak, Alan;Stefanovska, Aneta;Clarkson, Peter B. M.

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我们确定了 88 名健康受试者同时记录的微血管血流和氧饱和度信号之间的小波相位相干性,从而使我们能够研究它们的共同波动。在手臂和腿部的两个深度处进行了 30 分钟的测量。在皮肤中,血流和氧饱和度在心脏频率和低于 0.1Hz 直至大约 0.01Hz 时都是一致的。手臂的相干性延伸到比腿部的相干性更低的频率。从更深入的录音来看,两条肢体都没有发现一致性。皮肤血流和氧饱和度之间存在一致性,表明它们在一定频率范围内存在因果关系。该方法首次详细了解了血液氧合的动态。
We have determined the wavelet phase coherence between simultaneously recorded microvascular blood flow and oxygen saturation signals from 88 healthy subjects, thus enabling us to study their common fluctuations. Measurements were taken for 30min from the arm and leg, at two depths. In the skin, blood flow and oxygen saturation were found to be coherent both at the cardiac frequency and below 0.1Hz down to about 0.01Hz. Coherence in the arm extends to lower frequencies than that in the leg. From the deeper recordings, no coherence was found on either limb. The existence of coherence between skin blood flow and oxygen saturation demonstrates causal connections between them within certain frequency ranges. The method has yielded the first detailed insight into the dynamics of blood oxygenation.