COMPOSITE NATURE OF MONOSYNAPTIC EXCITATORY POSTSYNAPTIC POTENTIAL
COMPOSITE NATURE OF MONOSYNAPTIC EXCITATORY POSTSYNAPTIC POTENTIAL
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DOI：
10.1152/jn.1967.30.5.1114
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发表时间：
1967-01-01
影响因子：
2.5
通讯作者：
BURKE, RE
中科院分区：
文献类型：
--
作者：
BURKE, RE
观察了单支传入纤维兴奋性突触后电位（EPSP）和肌神经电刺激诱发的EPSP波形。微型EPSP的波形变化很大。这是由于在细胞膜上产生不同EPSP的突触位置的变化。有些组的突触终止于树突在相当大的电紧张距离的索马。电诱发的EPSP是由形状各异的微小突触电位总和组成的，因此树突和躯体位置也各不相同。电诱发EPSP的线性叠加也表明EPSP产生的活性部位具有广泛的空间分布。
The waveforms were examined of excitatory post synaptic potentials (EPSP''s) produced by activity in single la afferent fibers (miniature EPSP''s) and of the EPSP''s evoked by volleys produced electrically in muscle nerves. The miniature EPSP''s showed a wide variation in waveform. This was attributed to variation in the location of the synapses generating the different EPSP''s in the cell membrane. Some of the group la synapses terminated on dendrites at considerable electrotonic distances from the soma. The electrically evoked EPSP''s were composed of summated miniature synaptic potentials of widely varying shape and hence widely varying dendritic and somatic location. The linearity of summation of electrically evoked EPSP''s also suggested a wide spatial distribution of the active sites of EPSP generation.