Distinct brain areas process novel and repeating tone sequences
Distinct brain areas process novel and repeating tone sequences
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DOI：
10.1016/j.bandl.2018.09.006
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发表时间：
2018-12-01
影响因子：
2.5
通讯作者：
Rauschecker, Josef P.
中科院分区：
文献类型：
--
作者：
Green, Brannon;Jaaskelainen, Iiro P.;Rauschecker, Josef P.
听觉背向流与感觉运动整合和连续声音事件的串联有关，这两个过程对语音和音乐的处理都很重要。相比之下，听觉腹侧流的特征是从属于声音识别和识别。我们研究了背侧流和腹侧流，包括基底节和内侧颞叶结构的招募，在处理音调序列元素中的各自作用。在人类功能磁共振成像过程中，一个序列被递增地呈现在几次运行中，我们比较了第一次听到序列元素的激活(“新颖”)和元素重复时的激活(“熟悉”)。我们的结果表明，在将非常熟悉的序列元素编码成可识别的听觉对象后，在不太熟悉的序列元素的处理过程中，依赖于音调序列的激活从后背侧皮质区域和基底节转移到前部和腹侧皮质区域以及内侧颞叶。
The auditory dorsal stream has been implicated in sensorimotor integration and concatenation of sequential sound events, both being important for processing of speech and music. The auditory ventral stream, by contrast, is characterized as subserving sound identification and recognition. We studied the respective roles of the dorsal and ventral streams, including recruitment of basal ganglia and medial temporal lobe structures, in the processing of tone sequence elements. A sequence was presented incrementally across several runs during functional magnetic resonance imaging in humans, and we compared activation by sequence elements when heard for the first time ("novel") versus when the elements were repeating ("familiar"). Our results show a shift in tone sequence-dependent activation from posterior-dorsal cortical areas and the basal ganglia during the processing of less familiar sequence elements towards anterior and ventral cortical areas and the medial temporal lobe after the encoding of highly familiar sequence elements into identifiable auditory objects.