Intraosseous Versus Intravenous Access in Pediatric Septic Shock Patients Admitted to Alexandria University Pediatric Intensive Care Unit
Intraosseous Versus Intravenous Access in Pediatric Septic Shock Patients Admitted to Alexandria University Pediatric Intensive Care Unit
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DOI：
10.1093/tropej/fmx061
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发表时间：
2018-04-01
影响因子：
2
通讯作者：
Khalil, Mona
中科院分区：
文献类型：
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作者：
El-Nawawy, Ahmed A.;Omar, Omneya M.;Khalil, Mona
脓毒症急诊管理的基石是早期、目标导向的治疗。本研究的目的是评估骨内（IO）与静脉（IV）通道在儿科重症监护病房脓毒性休克患者复苏中的作用。本前瞻性介入随机临床试验研究对60例需要快速输液和药物治疗的感染性休克患者进行了研究；随机选择30例入路静脉通道，30例入路静脉通道。与IV组相比，IO组血管通路插入时间短，住院时间短，死亡率降低（p分别= 0.001,0.045,0.002）。在儿科急诊中，如休克情况下，建议使用IO路径以尽快获得快速血管通道，因为它显示出更好的结果。
The cornerstone of emergency management of sepsis is early, goal-directed therapy. The purpose of this study was to evaluate the effect of intraosseous (IO) vs. intravenous (IV) access for resuscitation of patients with septic shock admitted to pediatric intensive care unit. This prospective interventional randomized clinical trial study was conducted on 60 patients with septic shock who need rapid administration of fluids and drugs; 30 cases were randomly chosen for IO vascular access, while the other 30 were selected for IV access. The IO route was successfully secured in all cases with a significant shorter time of vascular access insertion, shorter length of stay and reduction in mortality in IO group vs. IV group (p = 0.001, 0.045, 0.002, respectively). In pediatric emergencies, as in case of shock, the use of IO route is recommended to get rapid vascular access as soon as possible, as it revealed better outcome.