Surveillance of nosocomial transmission of Candida albicans in an intensive care unit by DNA fingerprinting
Surveillance of nosocomial transmission of Candida albicans in an intensive care unit by DNA fingerprinting
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DOI：
10.1016/s0195-6701(03)00295-0
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发表时间：
2003-12-01
影响因子：
6.9
通讯作者：
Schröppel, K
中科院分区：
文献类型：
--
作者：
Taylor, BN;Harrer, T;Schröppel, K
应用中等重复序列Ca 3 DNA探针对32例重症监护病房患者的91株白色念珠菌进行了DNA指纹分析。这表明，C.来自个体患者的白色念珠菌属于遗传上不同的菌株。与医院感染的病原菌相比，C.重症监护室中的白色念珠菌发生频率要低得多。因此，C.白色念珠菌感染不在于医院内，而是在口腔分离株中。这些发现与感染控制实践有关。(C)2003年，医院感染协会。由爱思唯尔有限公司出版。保留所有权利。
The frequency of nosocomial transmission of the opportunistic fungal pathogen Candida albicans in an intensive care unit was tested by DNA fingerprinting of 91 isolates from 32 hospitalized patients with the midrepetitive Ca3 DNA probe. This showed that serial isolates of C. albicans from individual patients belonged to genetically distinct strains. In comparison with nosocomial bacterial pathogens, the transmission of C. albicans in an intensive care unit occurred at a much lower frequency. In conclusion, the threat of C. albicans infection does not lie within the hospital, but in commensal isolates. These findings are relevant for infection control practices. (C) 2003 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.