Individual Nanoparticle Detection in Liquids by Thermal Lens Microscopy and Improvement of Detection Efficiency Using a 1-μm Microfluidic Channel
Individual Nanoparticle Detection in Liquids by Thermal Lens Microscopy and Improvement of Detection Efficiency Using a 1-μm Microfluidic Channel
复制标题
通过热透镜显微镜检测液体中的单个纳米颗粒并使用 1 μm 微流体通道提高检测效率
作者：
N. Seta;K. Mawatari;T. Kitamori
纳米粒子由于其独特的物理化学性质，成为纳米科学和纳米技术中的关键材料，因此对分析方法的要求越来越高。在本研究中，我们开发了一种通过热透镜显微镜和微流控芯片检测单个纳米颗粒的方法。当纳米颗粒通过检测体积时，清楚地观察到脉冲信号。微流控通道的尺度从100 μm缩小到1 μm，提高了检测效率。结果，证明了100%的检测效率。
Nanoparticles are a key material in nanoscience and nanotechnology due to their unique physicochemical properties, so an analytical method is increasingly required. In the present research, we developed a method for individual nanoparticle detection by thermal lens microscopy and microfluidic chips. Pulsed signals were clearly observed, as nanoparticles were passing through the detection volume. The scale of the microfluidic channel was reduced from 100 to 1 μm to improve the detection efficiency. As a result, a detection efficiency of 100% was demonstrated.