Role of type 1 fimbriae in EPEC infections

Role of type 1 fimbriae in EPEC infections
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DOI:
10.1006/mpat.1997.0135
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发表时间:
1997-08-01
影响因子:
3.8
通讯作者:
Kaper, JB
Kaper, JB
中科院分区:
医学3区
文献类型:
--
作者:
Elliott, SJ;Kaper, JB

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一些纤维被认为在EPEC的粘附和发病机制中具有潜在的重要作用。EPEC菌株E2348/69仅产生成束丸和1型菌毛,不产生与EPEC菌株B171相同的其他附属黏附素。这些EPEC firn基因的克隆和诱变表明,1型药丸对培养的人细胞的粘附水平和模式没有影响。(C) 1997学术出版社有限公司
Several fimbriae have been implicated as potentially important in EPEC adhesion and pathogenesis. EPEC strain E2348/69 produced only bundle forming pill and type 1 fimbriae, and did not produce other accesory adhesins identified in EPEC strain B171. Cloning and mutagenesis of these EPEC firn genes indicated that type 1 pill had no affect on levels or patterns of adhesion to cultured human cells. (C) 1997 Academic Press Limited.