SIGNIFICANCE OF VENTRICULAR ARRHYTHMIAS INITIATED BY PROGRAMMED VENTRICULAR STIMULATION - THE IMPORTANCE OF THE TYPE OF VENTRICULAR ARRHYTHMIA INDUCED AND THE NUMBER OF PREMATURE STIMULI REQUIRED
SIGNIFICANCE OF VENTRICULAR ARRHYTHMIAS INITIATED BY PROGRAMMED VENTRICULAR STIMULATION - THE IMPORTANCE OF THE TYPE OF VENTRICULAR ARRHYTHMIA INDUCED AND THE NUMBER OF PREMATURE STIMULI REQUIRED
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DOI：
10.1161/01.cir.69.1.87
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发表时间：
1984-01-01
期刊：
影响因子：
37.8
通讯作者：
WELLENS, HJJ
中科院分区：
文献类型：
--
作者：
BRUGADA, P;GREEN, M;WELLENS, HJJ
在对有记录或疑似室性心律失常的患者进行心脏程序刺激期间，越来越多的室性早搏刺激被用于调查。为了分析引发的不同类型室性心律失常的重要性，对 52 名无室性心动过速或心室颤动患者（非 VT 组）和 50 名患者（既往 VT 组）记录了 1 至 4 次室性早搏刺激的影响进行了评估。既往 VT 组中超过一半的患者患有冠心病。在非 VT 组的大多数患者中，心脏是正常的。在既往 VT 组的 50 名患者中，有 44 名临床记录的室性心律失常是由心脏的程序性心室刺激引发的。在这 44 名患者中，88% 需要 1 或 2 次室性早搏才能引发临床心律失常。非 VT 组 52 名患者中有 31 名可能出现室性心律失常。室性心律失常包括非持续性单形性室性心动过速（2例）、6-25波持续性多形性室性心动过速（24例）和室颤（5例）。在非 VT 组中，70% 的患者需要 3 或 4 次室性早搏才能引发室性心律失常。显然，两组患者之间不仅引发室性心律失常所需的额外刺激数量不同，而且引发室性心律失常的类型也不同。非持续性多形性室性心动过速和心室颤动是对侵略性刺激方案的非特异性反应。
An increasing number of premature ventricular stimuli are being used during programmed stimulation of the heart in the investigation of patients with documented or suspected ventricular arrhythmias. To analyze the significance of the different types of ventricular arrhythmias that are initiated, the effects of from 1 to 4 ventricular premature stimuli were evaluated in 52 patients without (non-VT group) and 50 patients with (prior-VT group) documented ventricular tachycardia or ventricular fibrillation. More than half of the patients in the prior-VT group had coronary heart disease. In the majority of patients of the non-VT group the heart was normal. In 44 of the 50 patients in the prior-VT group the clinically documented ventricular arrhythmia was initiated by programmed ventricular stimulation of the heart. In 88% of these 44 patients, 1 or 2 ventricular premature beats were required to initiate the clinical arrhythmia. A ventricular arrhythmia could be initiated in 31 of the 52 patients in the non-VT group. The ventricular arrhythmias included nonsustained monomorphic ventricular tachycardia (2 patients), 6-25 complexes of sustained polymorphic ventricular tachycardia (24 patients) and ventricular fibrillation (5 patients). In 70% of patients in the non-VT group 3 or 4 ventricular premature beats were required to initiate the ventricular arrhythmia. Evidently, not only the number of extra stimuli required to initiate ventricular arrhythmias but also the type of venticular arrhythmia initiated differed between the 2 groups of patients. Nonsustained polymorphic ventricular tachycardia and ventricular fibrillation are nonspecific responses to aggressive stimulation protocols.