Controlled vapor deposition approach to generating substrate surface energy/chemistry gradients.
Controlled vapor deposition approach to generating substrate surface energy/chemistry gradients.
复制标题
产生基材表面能/化学梯度的受控气相沉积方法。
DOI：
10.1063/1.3594104
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
Thomas H. Epps
中科院分区：
文献类型：
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作者：
Julie N. L. Albert;Joey D. Kim;C. Stafford;Thomas H. Epps
衬底表面能量/化学梯度为高通量探索表面相互作用提供了一种手段，而表面相互作用在许多化学和生物过程中是重要的。我们描述了一种用于表面修饰的受控气相沉积方法的实现，该方法能够方便地产生衬底表面能量/化学梯度，同时保持梯度分布和表面化学的多功能性。在我们的系统中，梯度的形成依赖于在动态真空下，通过蒸发来自液体储存库的沉积材料，将功能化的氯硅烷交叉沉积到衬底表面。详细研究了储液器大小(储液器表面积)、储液器相对于衬底的位置、真空度和沉积材料的挥发度的影响，并证明了这种气相沉积方法提供的梯度可调谐程度。
Substrate surface energy/chemistry gradients provide a means for high-throughput exploration of the surface interactions that are important in many chemical and biological processes. We describe the implementation of a controlled vapor deposition approach to surface modification that enables the facile production of substrate surface energy/chemistry gradients while maintaining versatility in both the gradient profile and the surface chemistry. In our system, gradient formation relies on the cross-deposition of functionalized chlorosilanes onto the substrate surface via vaporization of the deposition materials from liquid reservoirs under dynamic vacuum. The effects of liquid reservoir size (reservoir surface area), reservoir position relative to the substrate, vacuum application, and volatility of the deposition materials are examined in detail and demonstrate the level of gradient tunability afforded by this vapor deposition approach.