Natural history of pancreatic intraductal papillary mucinous tumor of branch duct type - Follow-up study by magnetic resonance cholangiopancreatography
Natural history of pancreatic intraductal papillary mucinous tumor of branch duct type - Follow-up study by magnetic resonance cholangiopancreatography
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DOI：
10.1097/00004728-200401000-00020
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发表时间：
2004-01-01
影响因子：
1.3
通讯作者：
Honda, H
中科院分区：
文献类型：
--
作者：
Irie, H;Yoshimitsu, K;Honda, H
目的：本研究的目的是通过评估诊断为分支导管型胰腺导管内乳头状黏液性肿瘤（IPMT）患者的磁共振胰胆管造影（MRCP）结果的系列变化来阐明分支导管型胰腺导管内乳头状黏液性肿瘤（IPMT）的自然史。分支导管型IPMT 35例，其中9例为单独病变，并在超过12个月的时间内进行了初始和随访MRCP。对囊性病变的最大直径、相关主胰管（MPD）扩张的存在以及充盈缺损的存在进行了评价。结果：7例患者随访时MRCP显示肿瘤增大。在29个分支导管IPMT中，只有1个在最初的MRCP上没有发现相关的MPD扩张或充盈缺损，显示肿瘤逐渐增大。结论：分支导管型IPMT生长缓慢，只要肿瘤无MPD扩张或充盈缺损，可不经手术监测。
Objective: The purpose of this study was to elucidate the natural history of branch duct type pancreatic intraductal papillary mucinous tumor (IPMT) by evaluating serial changes in the magnetic resonance cholangiopancreatography (MRCP) findings of patients diagnosed with pancreatic IPMT of branch duct type.Methods: Thirty-five patients had branch duct type IPMT, including 9 patients with separate lesions, and underwent initial and followup MRCP over a period of more than 12 months. The maximum diameter of the cystic lesion, the presence of associated main pancreatic duct (MPD) dilatation, and the presence of a filling defect were evaluated. Serial changes in these findings were analyzed.Results: Tumor enlargement on follow-up MRCP was observed in 7 cases. Of the 29 branch duct IPMTs without associated MPD dilatation or a filling defect identified on initial MRCP, only 1 showed gradual tumor enlargement. In 4 cases, the cyst size decreased on follow-up MRCP.Conclusions: Branch duct type IPMTs grow slowly and can be monitored without operation provided that the tumor shows no associated MPD dilatation or filling defect.