Serological Measures of Malaria Transmission in Haiti: Comparison of Longitudinal and Cross-Sectional Methods
Serological Measures of Malaria Transmission in Haiti: Comparison of Longitudinal and Cross-Sectional Methods
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DOI：
10.1371/journal.pone.0093684
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发表时间：
2014-04-01
期刊：
影响因子：
3.7
通讯作者：
Lammie, Patrick J.
中科院分区：
文献类型：
--
作者：
Arnold, Benjamin F.;Priest, Jeffrey W.;Lammie, Patrick J.
背景：监测疟疾传播的努力越来越多地使用横断面调查，通过使用疟疾抗体的血清流行率数据来估计传播强度。迄今为止，横断面调查估计的血清转换率尚未与前瞻性队列估计的比率进行比较。我们的目的是比较在前瞻性队列中估计的血清转化率与在低传播人群中进行横断面调查的血清转化率。方法和发现：分析包括来自海地的两项研究：142名年龄儿童的前瞻性队列
Background: Efforts to monitor malaria transmission increasingly use cross-sectional surveys to estimate transmission intensity from seroprevalence data using malarial antibodies. To date, seroconversion rates estimated from cross-sectional surveys have not been compared to rates estimated in prospective cohorts. Our objective was to compare seroconversion rates estimated in a prospective cohort with those from a cross-sectional survey in a low-transmission population.Methods and Findings: The analysis included two studies from Haiti: a prospective cohort of 142 children ages