COVID-19 and COPD: a narrative review of the basic science and clinical outcomes.
COVID-19 and COPD: a narrative review of the basic science and clinical outcomes.
复制标题
DOI：
10.1183/16000617.0199-2020
复制
发表时间：
2020-12-31
期刊：
影响因子：
--
通讯作者：
Singh D
中科院分区：
文献类型：
--
作者：
Higham A;Mathioudakis A;Vestbo J;Singh D
2019年冠状病毒病(新冠肺炎)大流行是由严重急性呼吸综合征-冠状病毒-2(SARS-CoV-2)引起的。在男性、老年人和合并疾病的患者中，包括死亡率在内的临床结果更差。慢性阻塞性肺疾病患者被纳入屏蔽策略，因为他们对病毒引起的恶化、肺功能受损和相关合并症的高患病率易感。这篇综述利用基础科学和队列研究的证据，解决了关于新冠肺炎和慢性阻塞性肺病的关键问题。首先，是否存在COPD患者更容易感染SARS-CoV-2的机制？其次，吸入皮质类固醇对新冠肺炎有保护作用吗？第三，新冠肺炎对慢性阻塞性肺疾病患者的临床疗效有什么证据？这篇最新综述解决了在新冠肺炎背景下对慢性阻塞性肺疾病患者的长期前景有重大影响的一些关键问题。这篇最新综述在新冠肺炎https://bit.ly/36PKzEO的背景下解决了一些对慢性阻塞性肺疾病患者的长期前景有重大影响的关键问题
The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in males, older individuals and patients with comorbidities. COPD patients are included in shielding strategies due to their susceptibility to virus-induced exacerbations, compromised pulmonary function and high prevalence of associated comorbidities. Using evidence from basic science and cohort studies, this review addresses key questions concerning COVID-19 and COPD. First, are there mechanisms by which COPD patients are more susceptible to SARS-CoV-2 infection? Secondly, do inhaled corticosteroids offer protection against COVID-19? And, thirdly, what is the evidence regarding clinical outcomes from COVID-19 in COPD patients? This up-to-date review tackles some of the key issues which have significant impact on the long-term outlook for COPD patients in the context of COVID-19. This up-to-date review tackles some of the key issues which have significant impact on the long-term outlook for COPD patients in the context of COVID-19 https://bit.ly/36PKzEO
登录
查看更多内容
影响因子：
24.3
作者：
Chalmers, James D.;Laska, Irena F.;Miravitlles, Marc
通讯作者：
Miravitlles, Marc
DOI：
10.1164/rccm.201908-1550oc
发表时间：
2020-05-01
影响因子：
24.7
作者：
Angel Martinez-Garcia, Miguel;Faner, Rosa;Agusti, Alvar
通讯作者：
Agusti, Alvar
影响因子：
24.3
作者：
Cantoli, Marco;Pauletti, Alessia;Papi, Alberto
通讯作者：
Papi, Alberto
影响因子：
5.2
作者：
Benetti, Elisa;Tita, Rossella;Pinto, Anna Maria
通讯作者：
Pinto, Anna Maria
影响因子：
4.8
作者：
Douglas, GC;O'Bryan, MK;Lew, RA
通讯作者：
Lew, RA