Perioperative complications of hypothermia
Perioperative complications of hypothermia
复制标题
DOI：
10.1016/j.bpa.2008.07.005
复制
发表时间：
2008-12-01
影响因子：
4.8
通讯作者：
Kurz, Andrea
中科院分区：
文献类型：
--
作者：
Reynolds, Luke;Beckmann, James;Kurz, Andrea
围手术期体温过低是麻醉和手术的常见且严重的并发症，与许多不良围手术期结果相关。它可以延长吸入和静脉麻醉药的作用持续时间以及神经肌肉药物的作用持续时间。轻度核心体温过低会增加热不适感，并与麻醉后恢复延迟相关。轻度低温显着增加围手术期失血量并增加同种异体输血的需求。仅 1.9 摄氏度的核心低温就会使结肠切除术后手术伤口感染的发生率增加三倍，并使住院时间增加 20%。体温过低会对抗体和细胞介导的免疫防御以及周围伤口组织的氧气供应产生不利影响。此外，轻度低温会使术后不良心肌事件的发生率增加三倍。因此，即使是轻微的低温也会显着增加患者的护理成本，需要避免。
Perioperative hypothermia is a common and serious complication of anesthesia and surgery and is associated with many adverse perioperative outcomes. It prolongs the duration of action of inhaled and intravenous anesthetics as well as the duration of action of neuromuscular drugs. Mild core hypothermia increases thermal discomfort, and is associated with delayed post anaesthetic recovery. Mild hypothermia significantly increases perioperative blood loss and augments allogeneic transfusion requirement. Only 1.9 degrees C core hypothermia triples the incidence of surgical wound infection following colon resection and increases the duration of hospitalization by 20%. Hypothermia adversely affects antibody-and cell-mediated immune defences, as well as the oxygen availability in the peripheral wound tissues. Furthermore mild hypothermia triples the incidence of postoperative adverse myocardial events. Thus, even mild hypothermia contributes significantly to patient care costs and needs to be avoided.