Severe psychological distress among patients with epilepsy during the COVID-19 outbreak in southwest China
Severe psychological distress among patients with epilepsy during the COVID-19 outbreak in southwest China
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DOI：
10.1111/epi.16544
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发表时间：
2020-05-22
期刊：
影响因子：
5.6
通讯作者：
Yan, Bo
中科院分区：
文献类型：
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作者：
Hao, Xiaoting;Zhou, Dong;Yan, Bo
目的比较新冠肺炎疫情期间中国西南地区癫痫患者和健康对照者心理困扰的严重程度，以及确定癫痫患者严重心理困扰的潜在危险因素。方法本横断面病例-对照研究对2月1日至2010年2月30日在华西医院癫痫中心接受治疗的15岁以上患者进行了连续样本检查。2020年2月29日。作为对照组，在同一时期也招募了与住院患者（与患者无关）的性别和年龄匹配的健康访视者。通过在线问卷收集人口统计学数据和对COVID-19的关注，从电子病历中收集癫痫特征数据，并使用6项Kessler心理困扰量表（K-6）评估心理困扰。结果252例患者和252例对照组除家庭收入外，其他人口统计学变量沿着。癫痫患者的K-6评分显著高于健康对照组，并且在COVID-19爆发后花费的时间显著更多（均P < .001）。单变量分析将耐药性癫痫的诊断和关注COVID-19的时间与严重心理困扰（定义为K-6评分>12; P12均表示严重心理困扰）相关联。例如，这可能意味着鼓励患者从事其他活动，而不是过度关注媒体对疫情的报道。
Objective To compare the severity of psychological distress between patients with epilepsy and healthy controls during the COVID-19 outbreak in southwest China, as well as identify potential risk factors of severe psychological distress among patients with epilepsy.Methods This cross-sectional case-control study examined a consecutive sample of patients older than 15 years treated at the epilepsy center of West China Hospital between February 1 and February 29, 2020. As controls, sex- and age-matched healthy visitors of inpatients (unrelated to the patients) were also enrolled during the same period. Data on demographics and attention paid to COVID-19 were collected by online questionnaire, data on epilepsy features were collected from electronic medical records, and psychological distress was evaluated using the 6-item Kessler Psychological Distress Scale (K-6). Potential risk factors of severe psychological distress were identified using multivariate logistic regression.Results The 252 patients and 252 controls in this study were similar along all demographic variables except family income. Patients with epilepsy showed significantly higher K-6 scores than healthy controls and spent significantly more time following the COVID-19 outbreak (both P < .001). Univariate analyses associated both diagnosis of drug-resistant epilepsy and time spent paying attention to COVID-19 with severe psychological distress (defined as K-6 score >12; both P 12 indicate severe psychological distress. This may mean, for example, encouraging patients to engage in other activities instead of excessively following media coverage of the outbreak.