Association between miscellaneous symptoms and primary symptom dimensions among chinese adults with obsessive-compulsive disorder

Association between miscellaneous symptoms and primary symptom dimensions among chinese adults with obsessive-compulsive disorder
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中国成人强迫症杂症与主要症状维度的关联

DOI:
10.1016/j.psychres.2019.02.042
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发表时间:
2019-04
影响因子:
11.3
通讯作者:
Fan Qing
Fan Qing
中科院分区:
医学2区
文献类型:
--
作者:
Zhou Yuxin;Cao Xuan;Wang Jianyu;Gao Rui;Chen Yongjun;Liu Ying;Zhang Zongfeng;Wang Zhen;Storch Eric A.;Fan Qing

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强迫症(Obsessive Compulsive-Disorder,OCD)是一种常见的精神疾病,以强迫观念和/或强迫行为的存在为特征。症状的存在和严重程度通常通过耶鲁-布朗强迫症量表(Y-BOCS)进行评估。然而,嵌入在Y-BOCS症状检查表中的杂项症状尽管与某些维度相关,但往往被忽视。本研究采用探索性因素分析和Logistic回归分析的方法,对123名中国成人强迫症患者的各种症状与强迫症症状维度的关系进行了探讨。一个四维模型是factorially得出的:强迫症,对称性/random,污染/清洁和污染/清洁。一般而言,17个杂项症状中有11个与一个或多个症状维度相关。其中,强迫症维度与七种杂项症状显著相关:“害怕说不出正确的话”,“侵入性(非暴力)图像”,“侵入性无意义的声音,单词”等。污染/清洁维度与“需要了解或记住”相关。囤积/宗教维度与“害怕失去东西”和“迷信恐惧”有关。研究结果有助于中国强迫症患者的临床评估,诊断和治疗,了解在何种程度上,某些杂项症状与主要症状的尺寸。
Obsessive compulsive-disorder (OCD) is a common mental illness characterized by the presence of obsessions and/or compulsions. Symptom presence and severity is typically evaluated through the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). However, miscellaneous symptoms embedded within the Y-BOCS Symptom Checklist have often been overlooked despite being associated with certain dimensions. In this study, we used exploratory factor analysis and logistic regression to explore the relationship between various miscellaneous symptoms and OCD symptom dimensions among 123 Chinese adults with OCD. A four-dimensional model was factorially derived: Obsessions, Symmetry/Ritual, Contamination/Cleaning and Contamination/Cleaning. In general, 11 out of 17 miscellaneous symptoms were associated with one or more of the symptom dimensions. Among them, the Obsessions dimension was significantly associated with seven miscellaneous symptoms: “Fear of not saying just the right thing,” “Intrusive (non-violent) images,” “Intrusive nonsense sounds, words”, etc. The Symmetry/Ritual dimension was significantly associated with “Need to tell, ask, or confess.” The Contamination/Cleaning dimension was related to “Need to know or remember”. The Hoarding/Religion dimension was related to “Fear of losing things,” and “Superstitious fears”. Results contribute to the clinical assessment, diagnosis and treatment of Chinese patients with OCD by understanding the extent to which certain miscellaneous symptoms are associated with primary symptom dimensions.
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发表时间: 2009-09
影响因子: 5.5
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