Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature.
Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature.
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DOI：
10.1038/s41394-018-0134-z
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发表时间：
2018-01-01
影响因子：
1.2
通讯作者：
Kumari, Rima
中科院分区：
文献类型：
--
作者：
Singh, Ritika;Chaturvedi, Sujata;Kumari, Rima
简介：髓内神经鞘瘤仅占原发性脊柱肿瘤的0.3%。那些在圆锥是非常罕见的，特别是在没有神经纤维瘤病，只有12例报告在文献中，到目前为止，不包括本case.CASE介绍：我们报告的情况下，一个27岁的女性谁提出的投诉背痛自1年以来，在两个下肢的刺痛和麻木无力自6个月以来，和尿失禁自1个月。没有外伤或任何皮肤损伤的病史。脊柱磁共振成像（MRI）提供了室管膜瘤的临时诊断。病人进行了手术后，组织病理学显示它是一个神经鞘瘤。讨论：髓内神经鞘瘤没有神经纤维瘤病是非常罕见的圆锥，可以完全切除，除非有浸润。胶质瘤和室管膜瘤是该部位较常见的肿瘤，通常进行次全切除。这个病例强调了虽然非常罕见，神经鞘瘤的可能性可以在脊髓髓内病变的鉴别诊断中考虑。
INTRODUCTION: Schwannomas at an intramedullary location constitute only 0.3% of primary spinal tumors. Those in the conus are extremely rare, especially in the absence of neurofibromatosis, with only 12 cases reported in the literature so far, excluding the present case.CASE PRESENTATION: We report the case of a 27-year-old female who presented with complaints of backache since 1 year, weakness in both lower limbs with tingling and numbness since 6 months, and urinary incontinence since 1 month. There was no history of trauma or any skin lesions. Magnetic resonance imaging (MRI) of the spine provided a provisional diagnosis of ependymoma. The patient was operated upon, histopathology revealed it to be a schwannoma.DISCUSSION: Intramedullary schwannomas without neurofibromatosis are extremely rare at the conus and can be completely resected unless there is infiltration. Gliomas and ependymomas are commoner entities at this site, which are usually subtotally resected. This case highlights that although extremely rare, the possibility of a schwannoma may be considered in the differentials of an intramedullary spinal lesion.