Ablation Index for Catheter Ablation of Atrial Fibrillation - Clinical Applicability and Comparison With Force-Time Integral -
Ablation Index for Catheter Ablation of Atrial Fibrillation - Clinical Applicability and Comparison With Force-Time Integral -
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DOI：
10.1253/circj.cj-18-0361
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发表时间：
2018-11-01
影响因子：
3.3
通讯作者：
Tilz, Roland Richard
中科院分区：
文献类型：
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作者：
Muenkler, Paula;Kroeger, Stefan;Tilz, Roland Richard
背景：导管消融术中损伤形成的关键决定因素是贴靠力、射频（RF）功率和时间。本研究的目的是评估消融指数（AI），一种新的非线性公式的基础上，这些组件的临床适用性，并比较AI与传统的线性力-时间间隔（FTI）在肺静脉隔离（PVI）。对于最初的11例患者（A组），操作员在肺静脉隔离期间对AI设盲，对于其余23例患者（B组），操作员揭盲。我们评估了（1）AI的临床价值，以避免操作员对AI设盲与非设盲时的过高和过低值;以及（2）AI和FTI在预定范围内的关系。在A组中，235/564个病变（41.7%）在预定义的目标范围内，而B组中1，171/1，412个病变（82.9%）在预定义的目标范围内（P
Background: Key determinants for lesion formation in catheter ablation are contact force, radiofrequency (RF) power and time. The aim of this study was to evaluate the clinical applicability of ablation index (AI), a novel non-linear formula based on these components, and to compare AI with the conventional linear force-time interval (FTI) in pulmonary vein isolation (PVI).Methods and Results: Target AI ranges were defined for anatomical segments of the ipsilateral pulmonary veins. The operator was blinded to AI during PVI for the initial 11 patients (group A), and was unblinded for the remaining 23 patients (group B). We assessed (1) the clinical value of AI to avoid excessively high and low values with an operator blinded vs. non-blinded to AI; and (2) the relation of AI and FTI in predefined ranges. In group A, 235/564 lesions (41.7%) were in the predefined target range as compared with 1,171/1,412 lesions (82.9%) in group B (P