Action and object naming in Parkinson's disease without dementia
Action and object naming in Parkinson's disease without dementia
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DOI：
10.1111/j.1468-1331.2007.01797.x
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发表时间：
2007-06-01
影响因子：
5.1
通讯作者：
Padovani, A.
中科院分区：
文献类型：
--
作者：
Cotelli, M.;Borroni, B.;Padovani, A.
本研究旨在评估帕金森病（PD）患者的物体和动作命名能力。此外，我们希望评估一个特定的概念层面，即操纵性，对命名的对象和行动的效果。从布雷西亚大学神经病学系招募患者。根据已发表的标准，32名被诊断为PD，15名健康志愿者在年龄和教育程度上与患者样本相匹配。所有患者均接受了详细的临床和神经系统评估。动作-物体图片命名任务中使用的刺激来自美国医学研究中心-国际图片命名项目语料库。为了评估可操作性（或精细手部动作的参与）的影响，将名词-动词刺激重新分类为可操作和不可操作的项目（即，可以或不能操作的对象以及涉及或不涉及精细手部动作的动作）。与对照组相比，患者在动作和物体命名方面均表现出缺陷。此外，PD患者，但不是控制显着受损的行动比对象命名。目前的研究支持这样的观点，即PD患者的动作命名受到影响，可能反映了前额叶功能障碍的存在。
The present study aimed to assess the ability in objects and actions naming in Parkinson's disease (PD) patients. Further, we wished to assess the effect of a particular conceptual dimension, i.e. manipulability, on the naming of object and actions. Patients were recruited from the Department of Neurology, University of Brescia. Thirty-two were diagnosed as PD, according to published criteria, and 15 healthy volunteers matched in age and education to patients' sample. All patients underwent a detailed clinical and neurological evaluation. The stimuli used in the action-object picture naming task were taken from the Center for Research in Language-International Picture Naming Project corpus. To assess the effect of manipulability (or the involvement of fine hand movements) the noun-verb stimuli were re-categorized into manipulable and non-manipulable items (i.e. objects which can or cannot be manipulated and actions which do or do not involve fine hand movements). Patients showed a deficit both in action and object naming, compared with controls. In addition, patients with PD but not controls were significantly more impaired in action than in object naming. The current study supports the view that action naming is affected in patients with PD, possibly reflecting the presence of prefrontal dysfunction.