Cancer research across Africa: a comparative bibliometric analysis.

Cancer research across Africa: a comparative bibliometric analysis.
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DOI:
10.1136/bmjgh-2022-009849
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发表时间:
2022-11
期刊:
影响因子:
8.1
通讯作者:
Vanderpuye, Verna
Vanderpuye, Verna
中科院分区:
医学2区
文献类型:
--
作者:
Mutebi, Miriam;Lewison, Grant;Aggarwal, Ajay;Alatise, Olusegun Isaac;Booth, Christopher;Cira, Miska;Grover, Surbhi;Ginsburg, Ophira;Gralow, Julie;Gueye, Serine;Kithaka, Benda;Kingham, T. Peter;Kochbati, Lofti;Moodley, Jennifer;Mohammed, Sulma Ibrahim;Mutombo, Alex;Ndlovu, Ntokozo;Ntizimira, Christian;Parham, Groesbeck Preer;Walter, Fiona;Parkes, Jeannette;Shamely, Delva;Hammad, Nazik;Seeley, Janet;Torode, Julie;Sullivan, Richard;Vanderpuye, Verna

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研究是国家癌症控制规划的重要支柱。然而,各国缺乏实施可负担策略的证据。世界卫生组织和多个委员会建议根据客观数据开展基于利益相关者的需求评估,以生成证据,为国家和地区确定癌症研究需求和目标的优先次序提供信息。 开发并验证了文献计量算法(宏),用于评估所有54个非洲国家在12年期间(2009 - 2020年)的癌症研究成果。子分析包括合作模式、研究的部位和领域特定重点以及按职位和性别了解作者动态。进行了详细的子分析,以了解多个影响指标以及与疾病负担相比的相对产出情况,还应用了一个资助叙词表来确定资助资源。 在12年期间(2009 - 2020年),非洲国家总共发表了23679篇癌症研究论文,其中非洲的部分贡献总计为16201篇论文,其余7478篇来自非洲大陆以外的作者。论文总数随时间迅速增加,年增长率为15%。49个撒哈拉以南非洲(SSA)国家总共仅发表了5281篇论文,其中南非的贡献为2206篇(占SSA总数的42%,占全非洲的14%),尼日利亚的贡献为997篇(占SSA总数的19%,占全非洲的4%)。癌症研究占所有非洲生物医学研究成果的7.9%(非洲在传染病方面的研究是癌症研究的5.1倍)。在整个非洲,相对于其疾病负担而言,研究产出比例较低的是儿科癌症、宫颈癌、食管癌和前列腺癌。非洲的研究在其对发现科学和药物研究的关注方面反映了西方国家的情况。非洲女性研究人员的百分比与其他地方相当,但仅在北非和一些英语国家如此。 非洲大陆在相关本地研究成果的产生与癌症控制工作之间存在不平衡。根据这些数据,我们在五点计划中提出的建议主要集中在结构变革方面,例如,将研究明确纳入国家癌症控制规划;以及财政方面,例如,各国将国内生产总值的1%用于研究和开发的名义资金中的10%用于癌症研究。
Research is a critical pillar in national cancer control planning. However, there is a dearth of evidence for countries to implement affordable strategies. The WHO and various Commissions have recommended developing stakeholder-based needs assessments based on objective data to generate evidence to inform national and regional prioritisation of cancer research needs and goals. Bibliometric algorithms (macros) were developed and validated to assess cancer research outputs of all 54 African countries over a 12-year period (2009–2020). Subanalysis included collaboration patterns, site and domain-specific focus of research and understanding authorship dynamics by both position and sex. Detailed subanalysis was performed to understand multiple impact metrics and context relative outputs in comparison with the disease burden as well as the application of a funding thesaurus to determine funding resources. African countries in total published 23 679 cancer research papers over the 12-year period (2009–2020) with the fractional African contribution totalling 16 201 papers and the remaining 7478 from authors from out with the continent. The total number of papers increased rapidly with time, with an annual growth rate of 15%. The 49 sub-Saharan African (SSA) countries together published just 5281 papers, of which South Africa’s contribution was 2206 (42% of the SSA total, 14% of all Africa) and Nigeria’s contribution was 997 (19% of the SSA total, 4% of all Africa). Cancer research accounted for 7.9% of all African biomedical research outputs (African research in infectious diseases was 5.1 times than that of cancer research). Research outputs that are proportionally low relative to their burden across Africa are paediatric, cervical, oesophageal and prostate cancer. African research mirrored that of Western countries in terms of its focus on discovery science and pharmaceutical research. The percentages of female researchers in Africa were comparable with those elsewhere, but only in North African and some Anglophone countries. There is an imbalance in relevant local research generation on the continent and cancer control efforts. The recommendations articulated in our five-point plan arising from these data are broadly focused on structural changes, for example, overt inclusion of research into national cancer control planning and financial, for example, for countries to spend 10% of a notional 1% gross domestic expenditure on research and development on cancer.
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发表时间: 2020-04-27
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