Developing intrathoracic sentinel lymph node mapping with near-infrared fluorescent imaging in non-small cell lung cancer
Developing intrathoracic sentinel lymph node mapping with near-infrared fluorescent imaging in non-small cell lung cancer
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DOI：
10.1016/j.jtcvs.2012.05.072
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发表时间：
2012-09-01
影响因子：
6
通讯作者：
Colson, Yolonda L.
中科院分区：
文献类型：
--
作者：
Gilmore, Denis M.;Khullar, Onkar V.;Colson, Yolonda L.
由于生存率低和复发率高，早期肺癌目前似乎分期不足或治疗不足，或两者兼而有之。虽然前哨淋巴结活检是乳腺癌和黑色素瘤患者的标准，但其在非小细胞肺癌中的成功率并不可靠。前哨淋巴结活检可能有助于识别转移风险最大的淋巴结，并允许进行更详细的分析，以选择可能从辅助治疗中获益的患者。我们最近对早期肺癌患者进行的临床试验的早期结果表明，近红外成像可能为这些患者提供可靠的前哨淋巴结识别平台。（《胸血管外科杂志》2012;144：S80-4）
With poor survival and high recurrence rates, early-stage lung cancer currently appears to be understaged or un-dertreated, or both. Although sentinel lymph node biopsy is standard for patients with breast cancer and melanoma, its success has been unreliable in non-small cell lung cancer. Sentinel lymph node biopsy might aid in the identification of lymph nodes at the greatest risk of metastasis and allow for more detailed analysis to select for patients who might benefit from adjuvant therapy. The early results in our recent clinical trial of patients with early-stage lung cancer have suggested that near-infrared imaging might offer a platform for reliable sentinel lymph node identification in these patients. (J Thorac Cardiovasc Surg 2012;144:S80-4)